지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 217 - 220 (4page)
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초록· 키워드
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Background/Aims: The aim of this study was to evaluate the seroconversion rate of a hepatitis A virus (HAV) vaccination in patients with hepatitis B virus (HBV)-related chronic liver disease (CLD). Methods: Analyses were conducted using clinical records from 94 patients with chronic HBV infection who were seronegative for IgG anti-HAV antibodies between September 2008 and June 2009. Two doses of an HAV vaccine were administered 24 weeks apart. A third vaccine dose was administered only for patients seronegative for anti-HAV antibodies at week 48. Results: The seroconversion rate of anti-HAV following the two-dose vaccination was 86.17%. The seroconversion rate of anti-HAV was not signifi cantly different according to age or status of liver disease. The rate was higher in female than in male patients. A third HAV vaccine dose was administered to 13 patients seronegative for anti-HAV after the two-dose regimen, and 84.62% of these patients showed seroconversion at week 72. Conclusions: HAV vaccination is effective in most Korean patients with HBV-related CLD, and it might be necessary to evaluate three-dose vaccination approach for non-responders to the conventional regimen to maximize the success of an HAV vaccination program.
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참고문헌 (22)
참고문헌 신청
/ 1995 / Public health control of hepatitis A: memorandum from a WHO meeting / Bull World Health Organ 73 : 15 ~ 20
Advisory Committee on Immunization Practices (ACIP) / 1996 / Prevention of hepatitis A through active or passive immunization: recommendations of the Advisory Committee on I
Advisory Committee on Immunization Practices (ACIP) / 1999 / Prevention of hepatitis A through active or passive immunization: recommendations of the Advisory Committee on Im
Arguedas MR / 2001 / Immunogenicity of hepatitis A vaccination in decompensated cirrhotic patients / Hepatology 34 : 28 ~ 31
Bell BP / 1998 / The diverse patterns of hepatitis A epidemiology in the United States: implications for vaccination strategies / J Infect Dis 178 : 1579 ~ 1584
Advisory Committee on Immunization Practices (ACIP) / 1996 / Prevention of hepatitis A through active or passive immunization: recommendations of the Advisory Committee on I
Advisory Committee on Immunization Practices (ACIP) / 1999 / Prevention of hepatitis A through active or passive immunization: recommendations of the Advisory Committee on Im
Arguedas MR / 2001 / Immunogenicity of hepatitis A vaccination in decompensated cirrhotic patients / Hepatology 34 : 28 ~ 31
Bell BP / 1998 / The diverse patterns of hepatitis A epidemiology in the United States: implications for vaccination strategies / J Infect Dis 178 : 1579 ~ 1584
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