지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 284 - 289 (6page)
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초록· 키워드
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Background: Metabolic syndrome (MS) is a well-known risk factor of cardiovascular diseases that is focused on central obesity. Recent studies have reported the association between pericardial adipose tissue (PAT) volume and MS. However, no studies have demonstrated the cutoff PAT volume that represents the best association with MS.Methods: The data of 374 subjects were analyzed cross-sectionally to compare PAT, measured on coronary multi-detector computed tomography, and various metabolic parameters according to MS. After PAT volumes were di-vided into tertiles, various metabolic parameters were compared among tertiles; furthermore, the odds ratio for de-veloping MS was calculated. Finally, we demonstrated the cutoff PAT volume that represented the best association with MS by using the receiver-operating characteristic curve.Results: We found that 27.5% of the subjects had MS, and the mean PAT volume was 123.9 cm3. PAT showed a sig-nificant positive correlation with body mass index, waist circumference, and levels of glucose, triglyceride, high-sensitivity C-reactive protein, uric acid, and homocysteine, but a negative correlation with high-density lipoprotein cholesterol. Furthermore, after dividing into tertiles, PAT volume was also significantly associated with various met-abolic parameters. The odds ratio for having MS was 4.19 (95% confidence interval, 2.27–7.74) in the top tertile of PAT volumes after adjusting for age, sex, and smoking. The cutoff PAT volume that represented the best association with MS was 142.2 cm3.Conclusion: PAT was significantly associated with MS and various metabolic parameters. The cutoff PAT volume of 142.2 cm3 showed the best association with MS.
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참고문헌 (31)
참고문헌 신청
Grundy SM / 2005 / Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement / Circulation 112:2735~2752
Hubert HB / 1983 / Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study / Circulation 67:968~977
Meigs JB / 2006 / Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease / J Clin Endocrinol Metab 91:2906~2912
Yamaoka K / 2012 / Effects of lifestyle modification on metabolic syndrome: a systematic review and meta-analysis / BMC Med 10:138
Shin A / 2009 / Dietary intake, eating habits, and metabolic syndrome in Korean men / J Am Diet Assoc 109:633~640
Hubert HB / 1983 / Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study / Circulation 67:968~977
Meigs JB / 2006 / Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease / J Clin Endocrinol Metab 91:2906~2912
Yamaoka K / 2012 / Effects of lifestyle modification on metabolic syndrome: a systematic review and meta-analysis / BMC Med 10:138
Shin A / 2009 / Dietary intake, eating habits, and metabolic syndrome in Korean men / J Am Diet Assoc 109:633~640
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