지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 194 - 200 (7page)
이용수
초록· 키워드
오류제보하기
Eukaryotic gene expression is precisely regulated at all points between transcription and translation. In this review, we focus on translational control mediated by the 3’-untranslated regions (UTRs) of mRNAs. mRNA 3’-UTRs contain cis-acting elements that function in the regulation of protein translation or mRNA decay. Each RNA binding protein that binds to these cis-acting elements regulates mRNA translation via various mechanisms targeting the mRNA cap structure, the eukaryotic initiation factor 4E (eIF4E)-eIF4G complex, ribosomes, and the poly (A) tail. We also discuss translation-mediated regulation of mRNA fate.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Castello A / 2012 / Insights into RNA biology from an atlas of mammalian mRNAbinding proteins / Cell 149 : 1393 ~ 1406
Castello A / 2016 / Comprehensive Identification of RNA-Binding Domains in Human Cells / Mol Cell 63 : 696 ~ 710
Chen CA / 2017 / Emerging Themes in Regulation of Global mRNA Turnover in cis / Trends Biochem Sci 42 : 16 ~ 27
Cho PF / 2005 / A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP / Cell 121 : 411 ~ 423
Cho PF / 2006 / Cap-dependent translational inhibition establishes two opposing morphogen gradients in Drosophila embryos / Curr Biol 16 : 2035 ~ 2041
Castello A / 2016 / Comprehensive Identification of RNA-Binding Domains in Human Cells / Mol Cell 63 : 696 ~ 710
Chen CA / 2017 / Emerging Themes in Regulation of Global mRNA Turnover in cis / Trends Biochem Sci 42 : 16 ~ 27
Cho PF / 2005 / A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP / Cell 121 : 411 ~ 423
Cho PF / 2006 / Cap-dependent translational inhibition establishes two opposing morphogen gradients in Drosophila embryos / Curr Biol 16 : 2035 ~ 2041
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Optimization of mRNA 5"-untranslated Region for High Translation Efficiency
한국생물공학회 학술대회
2023 .04
-
Translation initiation mediated by nuclear cap-binding protein complex
BMB Reports
2017 .01
-
mRNA Mixed Tailing and Its Implication in mRNA Therapeutic
한국생물공학회 학술대회
2023 .10
-
Single-molecule visualization of mRNA circularization during translation
Experimental and Molecular Medicine
2023 .01
-
UTR(Untranslated Region) Engineering to Improve Recombinant Interferon-β Productivity in CHO Cells Under Low Temperature
한국생물공학회 학술대회
2021 .04
-
UTR (Untranslated Region) Optimization to Improve Recombinant Interferon-β1a Productivity in CHO Cells under Mild Hypothermia
한국생물공학회 학술대회
2021 .10
-
The emerging role of RNA modi fications in the regulation of mRNA stability
Experimental and Molecular Medicine
2020 .01
-
Two distinct nodes of translational inhibition in the Integrated Stress Response
BMB Reports
2017 .01
-
Method Development for mRNA Vaccine
한국생물공학회 학술대회
2023 .10
-
A new function of glucocorticoid receptor: regulation of mRNA stability
BMB Reports
2015 .01
-
Development of RNA Structures for the Development of Cancer Immunotherapeutic Vaccine System
한국고분자학회 학술대회 연구논문 초록집
2021 .04
-
5′ untranslated region of mRNA engineering for stable and enhanced gene expressions in Clostridium acetobutylicum
한국생물공학회 학술대회
2017 .10
-
Engineering Molecular Translation Systems
한국생물공학회 학술대회
2022 .04
-
A Novel mRNA Delivery System Using Self-Assembled Lipid Nanoparticles
한국생물공학회 학술대회
2022 .09
-
The Studies of mRNA Vaccine
한국생물공학회 학술대회
2020 .06
-
Synthetic mRNA Producing DNA Architecture
한국생물공학회 학술대회
2015 .04
-
Synthetic Protein Quality Control to Enhance Full-length Translation in Bacteria
한국생물공학회 학술대회
2021 .04
-
Functional Analysis of RNA Motifs Essential for BC200 RNA-mediated Translational Regulation
BMB Reports
2020 .01
-
5’-UTR 펩타이드의 발굴과 분석
한국정보과학회 학술발표논문집
2016 .12
이 논문의 저자 정보
최근 본 자료
댓글(0)
0