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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 167 - 173 (7page)
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초록· 키워드
오류제보하기
Experimental results obtained from research using only one sex are sometimes extrapolated to both sexes without thorough justification. However, this might cause enormous economic loss and unintended fatalities. Between years 1997 and 2000, the US Food and Drug Administration suspended ten prescription drugs producing severe adverse effects on the market. Eight of the ten drugs caused greater health risks in women. Serious male biases in basic, preclinical, and clinical research were the main reason for the problem. This mini-review will describe why and how funding organizations such as the European Commission, the Canadian Institutes of Health Research, and the US National Institutes of Health have tried to influence researchers to integrate sex/gender not only in clinical research, but also in basic and preclinical research. Editorial policies of prominent journals for sex-specific reporting will also be introduced, and some considerations in integrating sex as a biological variable will be pointed out. To produce precise and reproducible results applicable for both men and women, sex should be considered as an important biological variable from basic and preclinical research.
목차
등록된 정보가 없습니다.
참고문헌 (35)
참고문헌 신청
0000 / GAO-01-286R
Hughes RN / 2007 / Sex does matter: comments on the prevalence of male-only investigations of drug effects on rodent behaviour / Behav Pharmacol 18:583~589
GAO / 0000 / Women's Health-FDA Needs to Ensure More Study of Gender Differences in Prescription Drug Testing
Gochfeld M / 2017 / Sex Differences in Human and Animal Toxicology / Toxicol Pathol 45:172~189
Institute of Medicine / 2001 / Exploring the Biological Contributions to Human Health: Does Sex Matter?
Hughes RN / 2007 / Sex does matter: comments on the prevalence of male-only investigations of drug effects on rodent behaviour / Behav Pharmacol 18:583~589
GAO / 0000 / Women's Health-FDA Needs to Ensure More Study of Gender Differences in Prescription Drug Testing
Gochfeld M / 2017 / Sex Differences in Human and Animal Toxicology / Toxicol Pathol 45:172~189
Institute of Medicine / 2001 / Exploring the Biological Contributions to Human Health: Does Sex Matter?
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