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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 474 - 487 (14page)
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초록· 키워드
오류제보하기
Itch is one of the most distressing sensations that substantially impair quality of life. It is a cardinal symptom of many skin diseases and is also caused by a variety of systemic disorders. Unfortunately, currently available itch medications are ineffective in many chronic itch conditions, and they often cause undesirable side effects. To develop novel therapeutic strategies, it is essential to identify primary afferent neurons that selectively respond to itch mediators as well as the central nervous system components that process the sensation of itch and initiate behavioral responses. This review summarizes recent progress in the study of itch, focusing on itch-selective receptors, signaling molecules, neuronal pathways from the primary sensory neurons to the brain, and potential decoding mechanisms based on which itch is distinguished from pain.
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등록된 정보가 없습니다.
참고문헌 (151)
참고문헌 신청
Ikoma A / 2006 / The neurobiology of itch / Nat Rev Neurosci 7:535~547
Yosipovitch G / 2004 / Itch: basic mechanisms and therapy / CRC Press/Taylor & Francis
Misery L / 2010 / Pruritus / Springer
Williams HC / 2000 / Epidemiology of atopic dermatitis / Clin Exp Dermatol 25:522~529
Silverberg JI / 2016 / Addressing treatment challenges in atopic dermatitis with novel topical therapies / J Dermatolog Treat 11:1~9
Yosipovitch G / 2004 / Itch: basic mechanisms and therapy / CRC Press/Taylor & Francis
Misery L / 2010 / Pruritus / Springer
Williams HC / 2000 / Epidemiology of atopic dermatitis / Clin Exp Dermatol 25:522~529
Silverberg JI / 2016 / Addressing treatment challenges in atopic dermatitis with novel topical therapies / J Dermatolog Treat 11:1~9
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