지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 807 - 812 (6page)
이용수
초록· 키워드
오류제보하기
Background/Aims: Because of the poor prognosis of diffuse-type gastric cancer, early detection is important. We investigated the clinical characteristics and prognosis of diffuse-type early gastric cancer (EGC) diagnosed in subjects during health check-ups. Methods: Among 121,111 subjects who underwent gastroscopy during a routine health check-up, we identified 282 patients with 286 EGC lesions and reviewed their clinical and tumor-specific parameters. Results: Patients with diffuse-type EGC were younger, and 48.1% of them were female. Serum anti-Helicobacter pylori IgG (Hp-IgG) was positive in 90.7% of diffuse-type EGC patients (vs 75.9% of intestinal-type EGC, p=0.002), and the proportion of diffuse-type EGC cases increased significantly with increasing Hp-IgG serum titers (p<0.001). Diffuse-type EGC had pale discolorations on the tumor surface (26.4% vs 4.0% in intestinal-type EGC, p<0.001) and were often located in the middle third of the stomach. Submucosal invasion or regional nodal metastasis was observed more commonly in patients with diffuse-type EGC. However, during the median follow-up period of 50 months, 5-year disease-free survival rates did not differ between the groups. Conclusions: Diffuse-type EGC shows different clinical and endoscopic characteristics. Diffuse-type EGC is more closely associated with Hp-IgG seropositivity and a higher serum titer. Early detection results in excellent prognosis.
목차
등록된 정보가 없습니다.
참고문헌 (34)
참고문헌 신청
Hsu PI / 1997 / Correlation of serum immunoglobulin G Helicobacter pylori antibody titers with histologic and endoscopic findings in patients with dyspepsia / J Clin Gastroenterol 25:587~591
Kishikawa H / 2015 / Helicobacter pylori antibody titer and gastric cancer screening / Dis Markers 2015:156719
Ninomiya Y / 2000 / Unrecognizable intramucosal spread of diffuse-type mucosal gastric carcinomas of less than 20 mm in size / Endoscopy 32:604~608
Sawada S / 2010 / Expansion of indications for endoscopic treatment of undifferentiated mucosal gastric cancer: analysis of intramucosal spread in resected specimens / Dig Dis Sci 55:1376~1380
Adachi Y / 1993 / Microvascular architecture of early gastric carcinoma: microvascular-histopathologic correlates / Cancer 72:32~36
Kishikawa H / 2015 / Helicobacter pylori antibody titer and gastric cancer screening / Dis Markers 2015:156719
Ninomiya Y / 2000 / Unrecognizable intramucosal spread of diffuse-type mucosal gastric carcinomas of less than 20 mm in size / Endoscopy 32:604~608
Sawada S / 2010 / Expansion of indications for endoscopic treatment of undifferentiated mucosal gastric cancer: analysis of intramucosal spread in resected specimens / Dig Dis Sci 55:1376~1380
Adachi Y / 1993 / Microvascular architecture of early gastric carcinoma: microvascular-histopathologic correlates / Cancer 72:32~36
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