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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Purpose: Glufosinate ammonium poisoning can cause seizures, even after a symptom-free period. This study was conducted to evaluate the relationship between serum neuron specific enolase (NSE) level and the occurrence of seizures in patients with acute glufosinate ammonium poisoning. Methods: For this retrospective observational study, data from patients diagnosed with acute glufosinate ammonium poisoning were collected between January 2016 and June 2016. Serum NSE was measured within 2 hours of arrival at the emergency department. The patients were divided into a seizure group and a non-seizure group. Results: The seizure group included eight of the 15 total patients (53.3%). The serum NSE level was significantly higher in the seizure group than in the non-seizure group (32.4±11.9 ng/mL vs. 19.5±5 ng/mL, p=0.019). The amount of glufosinate ingested and initial and peak serum ammonia levels were significantly higher in the seizure group than in the non-seizure group. There was no significant difference in the area under the curve of the serum NSE level or the initial and peak serum ammonia levels in terms of predicting the occurrence of seizures. Conclusion: In acute glufosinate poisoning, initial serum NSE levels may help in prediction of seizures.
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참고문헌 (29)
참고문헌 신청
Ebert E / 1990 / Summary of safety evaluation toxicity studies of glufosinate ammonium / Food and Chemical Toxicology 28:339~349
Hirose Y / 1999 / A toxicokinetic analysis in a patient with acute glufosinate poisoning / Hum Exp Toxicol 18:305~308
이동건 / 2016 / Initial Serum Ammonia as a Predictor of Neurologic Complications in Patients with Acute Glufosinate Poisoning / Yonsei Medical Journal 57(1):254~259
Cha YS / 2017 / The relationship between serum ammonia level and neurologic complications in patients with acute glufosinate ammonium poisoning: A prospective observational study / Hum Exp Toxicol
Cakir Z / 2010 / S-$100{\beta}$ and neuron-specific enolase levels in carbon monoxide-related brain injury / The American journal of emergency medicine 28:61~67
Hirose Y / 1999 / A toxicokinetic analysis in a patient with acute glufosinate poisoning / Hum Exp Toxicol 18:305~308
이동건 / 2016 / Initial Serum Ammonia as a Predictor of Neurologic Complications in Patients with Acute Glufosinate Poisoning / Yonsei Medical Journal 57(1):254~259
Cha YS / 2017 / The relationship between serum ammonia level and neurologic complications in patients with acute glufosinate ammonium poisoning: A prospective observational study / Hum Exp Toxicol
Cakir Z / 2010 / S-
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