지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.8
- 수록면
- 259 - 270 (12page)
- DOI
- 10.7783/KJMCS.2019.27.4.259
이용수
초록· 키워드
오류제보하기
Background: Eucommia ulmoides has long been used as an herbal medicine for the treatment of diabetes, hypertension and other diseases in many Asian countries.
Methods and Results: This study aimed at evaluating the antioxidant and anti-inflammatory properties of its water (EU-DW, and REU-DW) and ethanol (EU-EtOH, and REU-EtOH) extracts, as well as those of non-roasted E. ulmoides (EU) and roasted EU (REU) cortex. The following were assessed in each extract: total phenolic and flavonoid contents, 1,1-diphenyl-2-picryl-hydrazyl (DPPH), 2,2"-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and nitrite radical scavenging activities, reducing power, DNA damage prevention activity, and nitric oxide (NO) inhibition activity. Both EU and REU extracts showed high phenolic and flavonoid content, dose-dependent DPPH radical scavenging capacity, high reducing activity, and considerable DNA damage prevention
activity. EU extracts showed remarkable ABTS free radicals scavenging capacity. REU extracts showed a higher radical scavenging capacity and played an important role in inhibiting NO production.
Conclusions: The results of this study suggested that aqueous and ethanol extracts of EU and REU possess antioxidant capacities, and prevent oxidative damage to DNA, probably owing to their phenolic and flavonoid content. Therefore, EU and REU could be candidates antioxidant supplements.
Methods and Results: This study aimed at evaluating the antioxidant and anti-inflammatory properties of its water (EU-DW, and REU-DW) and ethanol (EU-EtOH, and REU-EtOH) extracts, as well as those of non-roasted E. ulmoides (EU) and roasted EU (REU) cortex. The following were assessed in each extract: total phenolic and flavonoid contents, 1,1-diphenyl-2-picryl-hydrazyl (DPPH), 2,2"-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and nitrite radical scavenging activities, reducing power, DNA damage prevention activity, and nitric oxide (NO) inhibition activity. Both EU and REU extracts showed high phenolic and flavonoid content, dose-dependent DPPH radical scavenging capacity, high reducing activity, and considerable DNA damage prevention
activity. EU extracts showed remarkable ABTS free radicals scavenging capacity. REU extracts showed a higher radical scavenging capacity and played an important role in inhibiting NO production.
Conclusions: The results of this study suggested that aqueous and ethanol extracts of EU and REU possess antioxidant capacities, and prevent oxidative damage to DNA, probably owing to their phenolic and flavonoid content. Therefore, EU and REU could be candidates antioxidant supplements.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (36)
참고문헌 신청
Adedapo AA / 2009 / Assessment of the medicinal potentials of the methanol extracts of the leaves and stems of Buddleja saligna / BMC Complementary and Alternative Medicine 9:21
Ali SS / 2008 / Indian medicinal herbs as sources of antioxidants / Food Research International 41:1~15
Aruoma OI. / 1998 / Free radicals, oxidative stress, and antioxidants in human health and disease / Journal of the American Oil Chemists' Society 75:199~212
Babu D / 2013 / Antioxidant and free radical scavenging activity of triphala determined by using different in vitro models / Journal of Medicinal Plant Research 7:2898~2905
Beckman JS / 1996 / Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly / American Journal of Physiology-Cell Physiology 271:1424~1437
Ali SS / 2008 / Indian medicinal herbs as sources of antioxidants / Food Research International 41:1~15
Aruoma OI. / 1998 / Free radicals, oxidative stress, and antioxidants in human health and disease / Journal of the American Oil Chemists' Society 75:199~212
Babu D / 2013 / Antioxidant and free radical scavenging activity of triphala determined by using different in vitro models / Journal of Medicinal Plant Research 7:2898~2905
Beckman JS / 1996 / Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly / American Journal of Physiology-Cell Physiology 271:1424~1437
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