The survival impact of surgical waiting time in patients with resectable pancreatic head cancer

Hye Kyoung Seo; Dae Wook Hwang; Seo Young Park; Yejong Park; Seung Jae Lee; Jae Hoon Lee; Ki Byung Song; Young-Joo Lee; Song Cheol Kim

추천

검색

질문

자료유형: 학술저널

저자정보: Hye Kyoung Seo (University of Ulsan College of Medicine) Dae Wook Hwang (University of Ulsan College of Medicine) Seo Young Park (University of Ulsan College of Medicine) Yejong Park (University of Ulsan College of Medicine) Seung Jae Lee (University of Ulsan College of Medicine) Jae Hoon Lee (University of Ulsan College of Medicine) Ki Byung Song (University of Ulsan College of Medicine) Young-Joo Lee (University of Ulsan College of Medicine) Song Cheol Kim (University of Ulsan College of Medicine)

저널정보: 한국간담췌외과학회 Annals of Hepato-Biliary-Pancreatic Surgery 한국간담췌외과학회지 제22권 제4호

발행연도: 2018.11

수록면: 405 - 411 (7page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Backgrounds/Aims: After centralization policy, clinical outcomes have been improved in patients underwent pancreaticoduodenectomy for pancreatic cancer. However, centralization could exacerbate the prolongation of surgical waiting time. This study aims to investigate whether the shorter waiting time correlates with the better survival and to identify the major confounders that influence the association between those. Methods: In this retrospective cohort study, a total 554 patients with pathologically confirmed pancreatic ductal adenocarcinoma were assessed the eligibility from 2014 through 2015. Patients with neoadjuvant chemotherapy, body-tail resection, total pancreatectomy and combined adjacent organ resection were excluded. All patients were divided into two groups by median waiting time, 21 days, defined as the date difference between initial imaging diagnosis and operation. Results: Median overall survival did not differ between long and short waiting group (30.4 vs 24.8 months, p=0.35; HR=0.84, 95% CI=0.58-1.21). The proportion of cancer stage shifting, the difference between clinical and pathologic staging, did not differ depending on waiting time group (p=0.811 and 0.255, each of reviewers). Short waiting time was highly correlated with high initial clinical stage (Spearman correlation coefficients –0.201 (p=0.006) and –0.100 (p=0.175), each of reviewers). Conclusions: Initial clinical stage had confounding effect on the association between waiting time and overall survival. Therefore, in evaluating centralization policy at the national level, evidence for maximum acceptable waiting time should be investigated in the near future with considering that surgical waiting time could be affected by initial clinical stage.

#Pancreatic cancer #Pancreaticoduodenectomy #Waiting time #Survival

참고문헌 (0)

참고문헌 신청

참고문헌이 DBpia에서 서비스 중이라면, [참고문헌 신청]을 통해 등록해보세요

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!