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학술저널
저자정보
김유나 (인제대학교) 정도운 (인제대학교) 강제욱 (인제대학교) 문정준 (인제대학교) 전동욱 (인제대학교) 김성진 (인제대학교) 이윤호 (인제대학교) 박성용 (인제대학교) 이충열 (인제대학교)
저널정보
대한생물치료정신의학회 생물치료정신의학 생물치료정신의학 제24권 제2호(통권 제52호)
발행연도
2018.6
수록면
97 - 104 (8page)

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Objectives:The purpose of this study was to supplement the evaluation criteria for the schizophrenia disability grading system through a standardized test.
Methods:Patients with schizophrenia were divided into three groups according to their Global Assessment Function(GAF) scores, which correspond to the disability grade of schizophrenia. We evaluated and compared the functional outcomes of patients with schizophrenia belonging to different severity groups. We performed the UCSD Performance-Based Skills Assessment(UPSA) and GAF to assess functioning in daily life, and the Positive and Negative Syndrome Scale(PANSS) and Clinical Global Impression-Schizophrenia Scale(CGI-SCH) to assess clinical symptoms. One-way analysis of variance was used for comparison between the three groups. The correlation between UPSA and other scale scores was analyzed by Pearson’s correlation coefficient.
Results:A total of 117 patients were enrolled in this study. Of these, 46 were mild, 38 were moderate, and 33 were severe group. Significant differences in UPSA scores were identified between groups. The UPSA score was 71.54±14.12, 60.66±17.97, and 48.65±18.55 points for the mild, moderate, and severe group, respectively(p<0.001). The PANSS score was 53.83±15.67, 69.48±12.52, and 95.33±17.17 points for the mild, moderate, and severe group, respectively(p<0.001). The CGI-SCH score was 2.57±0.89, 3.08±0.94, and 4.18±1.01 points for the mild, moderate, and severe group, respectively(p<0.001). In addition, GAF, PANSS, and CGI-SCH showed a significant correlation with UPSA(correlation coefficient: 0.557, -0.497, and -0.570, respectively).
Conclusion:The UPSA is a useful tool for assessing functions of daily living in patients with schizophrenia, and can be used to systematically measure the functional ability of patients according to their disability grade.

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UCI(KEPA) : I410-ECN-0101-2018-512-002253209