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자료유형
학술저널
저자정보
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한국식품저장유통학회 Food Science and Preservation 한국식품저장유통학회지 제18권 제3호
발행연도
2011.6
수록면
358 - 365 (8page)

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The antioxidant and neuronal cell-protective effects of hot water extract from commercial buckwheat tea (CBTE) were evaluated. The 2,2`-azino-bis(3-ethyl-benzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, ferric reducing antioxidant power (FRAP), and malondialdehyde (MDA) inhibitory effect of the CBTE increased in a dose-dependent manner. The Intracellular reactive oxygen species (ROS) accumulation that resulted from hydrogen peroxide (H<sub>2</sub>O<SUB>2</SUB>) treatment more significantly decreased when CBTE was present in the media than when the PC12 cells were treated only with H<sub>2</sub>O<SUB>2</SUB>. In the neuronal cell viability assay using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyl-tetrazoliumbromide (MTT), the aqueous extracts showed a protective effect against H<sub>2</sub>O<SUB>2</SUB>-induced neurotoxicity, and the lactate dehydrogenase (LDH) release into the medium was also inhibited by CBTE. The total phenolics of CBTE was 9,608.10 mg/100 g, and the major phenolic compounds were rutin (13.42 mg/100 g) and quercitrin (0.90 mg/100 g). These data suggested that CBTE, including the aforementioned phenolics, may be useful in reducing the risk of neurodegenerative disease.

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