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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.4
- 수록면
- 226 - 235 (10page)
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This study was conducted to investigate the cholesterol lowering effect and weight reduction of autoclaved soy flour, cheonggukjang and doenjang, which are fermented using Bacillus subtilis DJI, in rats fed a high-fat/high-cholesterol diet. Male Sprague-Dawley rats weighing 250 g, were divided into five groups; a normal diet group (N), a high-fat/high-cholesterol diet group (HFC), a high-fat/high-cholesterol diet with 5% autoclaved soy flour group (HFC-S), a high-fat/high-cholesterol diet with 5% cheonggukjang group (HFC-CJ), and a high-fat/high-cholesterol diet with 5% deonjang group (HFC-DJ). The body weight gain and adipose tissues weights increased in rats fed a high-fat/high-cholesterol diet, but decreased significantly in rats fed autoclaved soy flour, cheonggukjang and doenjang, compared with the HFC group. Food intake was lower in the all HFC groups (HFC, HFC-S, HFC-CJ and HFC-DJ) than that of the N group, However, there was no differences in the food intake between HFC diet groups. Serum triglyceride level increased with a high-fat/high-cholesterol dietgroup whereas HFC-CJ and HFC-DJ groups were markedly decreased serum triglyceride levels compared with N group. Levels of serum total cholesterol and LDL-cholesterol, and level of total cholesterol in the liver were significantly lower in the HFC-S group, the HFC-CJ group and the HFC-DJ group than that of the HFC group, but exerted no significant change between the HFC groups on levels of total lipid and triglyceride in the liver. Fecal total lipid content increased in the HFC-CJ group and the HFC-DJ group than those of the HFC group and HFC-S group. The activities of heparin-releasable lipoprotein lipase (HR-LPL) and total-extractable LPL in adipose tissues decreased in the HFC-S group, the HFC-CJ group and the HFC-DJ group compared with the HFC group. These results suggest that dietary cheonggukjang and doenjang may exert cholesterol-lowering effect and prevent obesity.
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참고문헌 (40)
참고문헌 신청
1. [보고서] - Korea National Statistical Office / 2004 / Annual report on the cause of death statics : 23 ~
2. [학술지(정기간행물)] - Nordmann R / 1990 / Ethanol induced lipid peroxidation and oxidative stress in extrahepatic tissues / Alcohol 25 : 231 ~ 237
3. [학술지(정기간행물)] - Kim JK / 1990 / Study on identification of normal serum cholesterol level for prevention of atherosclerosis in Koreans / Korean J Medicine 33 : 12 ~ 20
4. [학술지(정기간행물)] - Janes PJ / 1993 / Meal-frequency effects on plasma hormone concentrations and cholesterol synthesis in humans / Am J Clin Nutr 57 : 868 ~ 874
5. [학술지(정기간행물)] - Phinney SD / 1990 / Reduced arachidonate in serum phospholipids and cholesteryl esters associated with vegetarian diets in human / Am J Clin Nutr 51 : 385 ~ 392
2. [학술지(정기간행물)] - Nordmann R / 1990 / Ethanol induced lipid peroxidation and oxidative stress in extrahepatic tissues / Alcohol 25 : 231 ~ 237
3. [학술지(정기간행물)] - Kim JK / 1990 / Study on identification of normal serum cholesterol level for prevention of atherosclerosis in Koreans / Korean J Medicine 33 : 12 ~ 20
4. [학술지(정기간행물)] - Janes PJ / 1993 / Meal-frequency effects on plasma hormone concentrations and cholesterol synthesis in humans / Am J Clin Nutr 57 : 868 ~ 874
5. [학술지(정기간행물)] - Phinney SD / 1990 / Reduced arachidonate in serum phospholipids and cholesteryl esters associated with vegetarian diets in human / Am J Clin Nutr 51 : 385 ~ 392
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