지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.7
- 수록면
- 161 - 166 (6page)
이용수
초록· 키워드
오류제보하기
Ginseng is widely used for its promising healing and restorative properties as well as for its possible tonic effect in traditional medicine. Nowadays, many studies focus on purified individual ginsenoside, an important constituent in ginseng, and study its specific mechanism of action instead of whole-plant extracts on cardiovascular diseases (CVDs). Of the various ginsenosides, purified ginsenosides such as Rb1, Rg1, Rg3, Rh1, Re, and Rd are the most frequently studied. Although there are many reports on the molecular mechanisms and medical applications of ginsenosides in the treatment of CVDs, many concerns exist in their application. This review discusses current works on the countless pharmacological functions and the potential benefits of ginseng in the area of CVDs. Results: Both in vitro and in vivo results indicate that ginseng has potentially positive effects on heart disease through its various properties including antioxidation, reduced platelet adhesion, vasomotor regulation, improving lipid profiles, and influencing various ion channels. To date, approximately 40 ginsenosides have been identified, and each has a different mechanism of action owing to the differences in chemical structure. This review aims to present comprehensive information on the traditional uses, phytochemistry, and pharmacology of ginseng, especially in the control of hypertension and cardiovascular function. In addition, the review also provides an insight into the opportunities for future research and development on the biological activities of ginseng.
목차
abstract
1. Introduction
2. Efficacy of ginseng in improving circulation and antioxidant activity
3. Efficacy of ginseng in modulating vascular function
4. Efficacy of ginseng in adjusting vasomotor functions
5. Efficacy of ginseng in improving cardiac functions
6. Efficacy of ginseng in inhibiting platelet aggregation
7. Efficacy of ginseng in adjusting lipid profile
8. Efficacy of ginseng in regulating Ca2+ channels
9. Concluding remarks
References
참고문헌 (89)
참고문헌 신청
1. [학술지(정기간행물)] - Gielen S / 2014 / The Year in Cardiology 2013 : cardiovascular disease prevention / Eur Heart J 35 : 307 ~ 312
2. [학술지(정기간행물)] - 임규희 / 2013 / Cardioprotective potential of Korean Red Ginseng extract on isoproterenol-induced cardiac injury in rats / Journal of Ginseng Research 37 (3) : 273 ~ 282
3. [학술지(정기간행물)] - Tunstall-Pedoe H / 2000 / Estimation of contribution of changes in coronary care to improving survival, event rates, and coronary heart disease mortality across the WHO MONICA Project populations / Lancet 355 : 688 ~ 700
4. [학술지(정기간행물)] - Toth PP / 2007 / Making a case for quantitative assessment of cardiovascular risk / J Clin Lipidol 1 : 234 ~ 241
5. [학술지(정기간행물)] - Libby P / 2005 / Act local, act global: inflammation and the multiplicity of 'vulnerable' coronary plaques / J Am Coll Cardiol 45 : 1600 ~ 1602
2. [학술지(정기간행물)] - 임규희 / 2013 / Cardioprotective potential of Korean Red Ginseng extract on isoproterenol-induced cardiac injury in rats / Journal of Ginseng Research 37 (3) : 273 ~ 282
3. [학술지(정기간행물)] - Tunstall-Pedoe H / 2000 / Estimation of contribution of changes in coronary care to improving survival, event rates, and coronary heart disease mortality across the WHO MONICA Project populations / Lancet 355 : 688 ~ 700
4. [학술지(정기간행물)] - Toth PP / 2007 / Making a case for quantitative assessment of cardiovascular risk / J Clin Lipidol 1 : 234 ~ 241
5. [학술지(정기간행물)] - Libby P / 2005 / Act local, act global: inflammation and the multiplicity of 'vulnerable' coronary plaques / J Am Coll Cardiol 45 : 1600 ~ 1602
이 논문의 저자 정보
이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2018-524-001597282