지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.9
- 수록면
- 357 - 366 (10page)
- DOI
- 10.17548/ksaf.2017.09.30.357
이용수
초록· 키워드
오류제보하기
The self-similarity and recursiveness, characteristics of fractal, can be said to be the basic principle of life phenomena which can be defined as organizing the order or pattern internally by exchanging energy with external environment.
A bio-organism is a chaos itself where the self-similarity of the microstructure and the amorphous fractal of the macrostructure are mixed. The structural difference are discussed at micro and macroscopic level. Self-similarity of subcellular organisms such as virus, viroid and prion is also discussed. The hierarchical structures of biomacromolecules such as DNA, RNA and protein are also reviewed.
Extensive researches on the diagnosis and prevention of diseases by fractal dimension analysis are carried out. Some cases of fractal dimension analysis related to human disease such as Parkinson’s disease, Alzheimer’s dementia, heart failure, and cancer, etc are discussed. Cases of fractal dimension analysis related to apoptosis are also discussed.
Whether information about morphogenesis of a bio-organism is included in the genome or not is in controversy up to now and the interpretation of the information about morphogenesis is very complex and seems to have limitations in analyzing complete patterns by existing molecular biological techniques.
Fractal dimension analysis is, based on recent researches, considered to be useful enough to complement molecular biological techniques as a quantitative analysis tool for various life phenomena including human disease diagnosis in post genome era.
A bio-organism is a chaos itself where the self-similarity of the microstructure and the amorphous fractal of the macrostructure are mixed. The structural difference are discussed at micro and macroscopic level. Self-similarity of subcellular organisms such as virus, viroid and prion is also discussed. The hierarchical structures of biomacromolecules such as DNA, RNA and protein are also reviewed.
Extensive researches on the diagnosis and prevention of diseases by fractal dimension analysis are carried out. Some cases of fractal dimension analysis related to human disease such as Parkinson’s disease, Alzheimer’s dementia, heart failure, and cancer, etc are discussed. Cases of fractal dimension analysis related to apoptosis are also discussed.
Whether information about morphogenesis of a bio-organism is included in the genome or not is in controversy up to now and the interpretation of the information about morphogenesis is very complex and seems to have limitations in analyzing complete patterns by existing molecular biological techniques.
Fractal dimension analysis is, based on recent researches, considered to be useful enough to complement molecular biological techniques as a quantitative analysis tool for various life phenomena including human disease diagnosis in post genome era.
목차
Abstract
Ⅰ. Introduction
Ⅱ. Chaotic Structure of Organisms
Ⅲ. Hierarchical Structure of Biomolecules at Microscopic Level
Ⅳ. Fractals as a Quantitative Analysis Tool for Human Disease Diagnosis
Ⅴ. Concluding Remarks
Reference
참고문헌 (27)
참고문헌 신청
[학술지(정기간행물)] - Agnati, L. F. / 2009 / Mosaic, Self-similarity logic and biological attraction principles / Communicative and Integrative biology 2 (6) : 552 ~ 563
[학술지(정기간행물)] - Aon, M.A / 1994 / On the fractal nature of cytoplasm / FEBS Letters 344 : 1 ~ 4
[학술지(정기간행물)] - Baish, J.W / 2000 / Fractals and Cancer / Cancer Res 60 : 3683 ~ 3688
[학술지(정기간행물)] - Bru, A. / 2003 / The Universal Dynamics of Tumor Growth / Biophysical Journal 85 : 2948 ~ 2961
[학술지(정기간행물)] - Cheung, N. / 2010 / Retinal fractals and acute lacunar stroke / Ann. Neurol 68 (1) : 107 ~ 111
[학술지(정기간행물)] - Aon, M.A / 1994 / On the fractal nature of cytoplasm / FEBS Letters 344 : 1 ~ 4
[학술지(정기간행물)] - Baish, J.W / 2000 / Fractals and Cancer / Cancer Res 60 : 3683 ~ 3688
[학술지(정기간행물)] - Bru, A. / 2003 / The Universal Dynamics of Tumor Growth / Biophysical Journal 85 : 2948 ~ 2961
[학술지(정기간행물)] - Cheung, N. / 2010 / Retinal fractals and acute lacunar stroke / Ann. Neurol 68 (1) : 107 ~ 111
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UCI(KEPA) : I410-ECN-0101-2018-600-001335747