지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.9
- 수록면
- 59 - 70 (12page)
- DOI
- 10.14367/kjhep.2017.34.3.59
이용수
초록· 키워드
오류제보하기
Objectives: This study was performed to determine the relationship between abnormal liver function and metabolic risk factors in obese children and adolescents. Methods: The participants were 118,830 obese children and adolescents who received health examinations for students supervised by Korean Ministry of Education and conducted by the Korea Association of Health Promotion in 2006-2015. Obesity were evaluated by relative weight, and the metabolic risk factors consisted of blood pressure, fasting blood sugar, and total cholesterol. ‘Abnormal liver function’ was defined by ALT and AST. The association of ‘Abnormal liver function’ with metabolic risk factors were explored after adjusting for sex and grade of school, by using multivariate logistic regression analysis. Results: The factors significantly associated with abnormal liver function were degrees of obesity, blood pressure, fasting blood sugar, and total cholesterol. Severe obesity had highest odds ratio of 4.92 (95% Confidence Intervals, 4.66-5.20; p<.001) among the metabolic risk factors. Conclusions: Metabolic risk factors had a significant impact on abnormal liver function. In order to prevent non-alcoholic fatty liver disease in obese children and adolescents, it is most important to lose weight and it is also necessary to manage risk factors through regular health examinations and lifestyle intervention.
목차
Ⅰ. 서론
Ⅱ. 연구방법
Ⅲ. 연구결과
Ⅳ. 논의
Ⅴ. 결론
References
참고문헌 (33)
참고문헌 신청
Alp, H., Karaarslan, S., Eklioglu, B. S., Atabek, M. E., Altin, H., & Baysal, T. (2013). Association between nonalcoholic fatty liver disease and cardiovascular risk in obese children and adolescents. Canadian Journal of Cardiology, 29, 1118-1125.
Alterio, A., Alisi, A., Liccrdo, D., Nobili, V. (2014). Non-alcholoic fatty liver and metabolic syndrome in children: A vicious circle, Hormone research in paediatrics, 82(5), 283-289.
Anderson, E. L., Howe, L. D., Jones, H. E., Higgins, J. P. T., Lawlor, D. A., & Fraser, A. (2015). The prevalence of non-alcoholic fatty liver disease in children and adolescents: a systematic review and meta-analysis. PLoS ONE, 10(10), e0140908.
Burgert, T. S., Taksali, S. E., Dziura, J., Goodman, T. R., Yeckel, C. W., Papademetris, X., . . ., Caprio, S.(2006). Alanine aminotransferase levels and fatty liver in childhood obesity: Associations with insulin resistance, adiponectin, and visceral fat, The Journal of Clinical Endocrinology & Metabolism, 91(11), 4287-4294.
Ciocca, M., Ramonet, M., & Avarez, F. (2016) Non-alcoholic fatty liver disease: a new epidemic in children. Archivos Argentinos de Pediatria, 114(6), 563-569.
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UCI(KEPA) : I410-ECN-0101-2018-517-001341854