지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.22 No.2
- 발행연도
- 2017.6
- 수록면
- 144 - 148 (5page)
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초록· 키워드
오류제보하기
Sulfites are used as food preservatives and excessive sulfite might disturb the body systems including the brain. Curcumin shows protective effects on the nervous system toxicity. The present study aimed to evaluate the protective role of curcumin in sulfite-induced anxiety in rats. Male rats were divided into five groups. The rats in groups I to V received distilled water (vehicle of sulfite, 1 mL/d), olive oil (vehicle of curcumin, 1 mL/d), curcumin (100 mg/kg/d), sulfite (25 mg/kg/d), and sulfite+curcumin, respectively, by daily gastric gavage for 8 weeks. At the end of 8 weeks the rats were tested in the elevated plus-maze for anxiety. The results showed that concomitant treatment of curcumin during sulfite consumption prevented the reduction of the time spent in the open arm and entrance to the open arm (the indexes of anxiety). Besides, an increase was found in motor activity of the rats in the sulfite+curcumin group compared to the sulfite- treated animals. Exposure of sulfite in rats can induce anxiety, and curcumin can act as an anti-anxiety agent.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (41)
참고문헌 신청
[학술지(정기간행물)] - Kencebay C / 2013 / Merit of quinacrine in the decrease of ingested sulfite-induced toxic action in rat brain / Food Chem Toxicol 52 : 129 ~ 136
[학술지(정기간행물)] - Gunnison AF / 1987 / Sulfite hypersensitivity. A critical review / CRC Crit Rev Toxicol 17 : 185 ~ 214
[학술지(정기간행물)] - Gunnison AF / 1971 / Sulfur dioxide : sulfite. Interaction with mammalian serum and plasma / Arch Environ Health 22 : 381 ~ 388
[학술지(정기간행물)] - Gunnison AF / 1981 / Sulphite toxicity : a critical review of in vitro and in vivo data / Food Cosmet Toxicol 19 : 667 ~ 682
[학술지(정기간행물)] - Mottley C / 1988 / Sulfate anion free radical formation by the peroxidation of(Bi)sulfite and its reaction with hydroxyl radical scavengers / Arch Biochem Biophys 267 : 681 ~ 689
[학술지(정기간행물)] - Gunnison AF / 1987 / Sulfite hypersensitivity. A critical review / CRC Crit Rev Toxicol 17 : 185 ~ 214
[학술지(정기간행물)] - Gunnison AF / 1971 / Sulfur dioxide : sulfite. Interaction with mammalian serum and plasma / Arch Environ Health 22 : 381 ~ 388
[학술지(정기간행물)] - Gunnison AF / 1981 / Sulphite toxicity : a critical review of in vitro and in vivo data / Food Cosmet Toxicol 19 : 667 ~ 682
[학술지(정기간행물)] - Mottley C / 1988 / Sulfate anion free radical formation by the peroxidation of(Bi)sulfite and its reaction with hydroxyl radical scavengers / Arch Biochem Biophys 267 : 681 ~ 689
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