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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.92 No.4
- 발행연도
- 2017.4
- 수록면
- 191 - 199 (9page)
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초록· 키워드
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Purpose: The aim of this study was to investigate survival in patients aged ≥70 years who underwent colorectal cancer surgery in 2003 and 2009. In addition, we aimed to identify the factors that could affect survival in these patients.
Methods: In a cross-sectional study, a retrospective review of the data for 878 patients ho underwent colorectal cancer surgery with curative intent in the years 2003 and 2009 was performed. The primary outcome was the 5-year overall survival rate (5-OSR), and he clinicopathologic factors that could affect overall survival were analyzed.
Results: The 5-OSR was 77.8% and 84.9% in 2003 and 2009, respectively (P = 0.013). Age, American Society of Anesthesiologists physical status classification, stage, type of surgery, and length of hospital stay possibly affected survival per the univariate and multivariate analyses. In patients aged ≥70 years, the 5-OSR in 2009 was 75.9%, which showed improvement compared to 53.7% in 2003 (P = 0.027). The stage, type of surgery, and hospital stay were the variables that possibly affected survival in patients aged ≥70 years per the univariate analysis, whereas the stage (III; hazard ratio [HR], 2.188; P = 0.005) and length of hospital stay (>12 days; HR, 2.307; P = 0.004), were the variables that showed statistical significance on the multivariate analysis.
Conclusion: We found that early stage and shortening the length of hospital stay could affect survival in older patients with colorectal cancers. Because of limited evidence on the influence of shortening the length of hospital stay on survival in older patients, further investigations are warranted.
Methods: In a cross-sectional study, a retrospective review of the data for 878 patients ho underwent colorectal cancer surgery with curative intent in the years 2003 and 2009 was performed. The primary outcome was the 5-year overall survival rate (5-OSR), and he clinicopathologic factors that could affect overall survival were analyzed.
Results: The 5-OSR was 77.8% and 84.9% in 2003 and 2009, respectively (P = 0.013). Age, American Society of Anesthesiologists physical status classification, stage, type of surgery, and length of hospital stay possibly affected survival per the univariate and multivariate analyses. In patients aged ≥70 years, the 5-OSR in 2009 was 75.9%, which showed improvement compared to 53.7% in 2003 (P = 0.027). The stage, type of surgery, and hospital stay were the variables that possibly affected survival in patients aged ≥70 years per the univariate analysis, whereas the stage (III; hazard ratio [HR], 2.188; P = 0.005) and length of hospital stay (>12 days; HR, 2.307; P = 0.004), were the variables that showed statistical significance on the multivariate analysis.
Conclusion: We found that early stage and shortening the length of hospital stay could affect survival in older patients with colorectal cancers. Because of limited evidence on the influence of shortening the length of hospital stay on survival in older patients, further investigations are warranted.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (23)
참고문헌 신청
[학술지(정기간행물)] - Turrentine FE / 2006 / Surgical risk factors, morbidity, and mortality in elderly patients / J Am Coll Surg 203 : 865 ~ 877
[학술지(정기간행물)] - Alves A / 2005 / Postoperative mortality and morbidity in French patients undergoing colorectal surgery : results of a prospective multicenter study / Arch Surg 140 : 278 ~ 283
[학술지(정기간행물)] - Yang Z / 2014 / Clinicopathological characteristics and long-term outcomes of colorectal cancer in elderly Chinese patients undergoing potentially curative surgery / Surg Today 44 : 115 ~ 122
[학술지(정기간행물)] - Story DA. / 2008 / Postoperative complications in elderly patients and their significance for long-term prognosis / Curr Opin Anaesthesiol 21 : 375 ~ 379
[학술지(정기간행물)] - 정규원 / 2015 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2012 / Cancer Research and Treatment 47 (2) : 127 ~ 141
[학술지(정기간행물)] - Alves A / 2005 / Postoperative mortality and morbidity in French patients undergoing colorectal surgery : results of a prospective multicenter study / Arch Surg 140 : 278 ~ 283
[학술지(정기간행물)] - Yang Z / 2014 / Clinicopathological characteristics and long-term outcomes of colorectal cancer in elderly Chinese patients undergoing potentially curative surgery / Surg Today 44 : 115 ~ 122
[학술지(정기간행물)] - Story DA. / 2008 / Postoperative complications in elderly patients and their significance for long-term prognosis / Curr Opin Anaesthesiol 21 : 375 ~ 379
[학술지(정기간행물)] - 정규원 / 2015 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2012 / Cancer Research and Treatment 47 (2) : 127 ~ 141
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UCI(KEPA) : I410-ECN-0101-2017-514-002372376