지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Epigenomics is a study that analyzes and quantifies various epigenetic alterations that affect gene expressions in cells from the viewpoint of collective characteristics on biological molecular pools. DNA methylation and histone modification in cells can induce the epigenetic alterations. Especially, epigenetic alterations influenced by external factors such as ingested foods and other environmental factors have been examined in the whole genome regions, which provide accumulated data of altered regions or patterns of global genome. Statistical analyses of these regions or patterns enables us to correlate epigenomic changes with human diseases in the whole genome region. Finding meaningful regulators is a major concern of epigenomic research in recent years, and these results will give the food industry an important clue to future food.
목차
Abstract
1. 서론
2. Epigenetic 변화
3. 식품에 의한 epigenetic modification
4. 결론
감사의 글
참고문헌
참고문헌 (26)
참고문헌 신청
Wolffe AP / 1999 / Epigenetics : regulation through repression / Science 286:481~486
Li Y / 2010 / Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research / Pharm. Res 27:1027~1041
Li Y / 2010 / Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components / Curr. Med. Chem 17:2141~2151
Winter J / 2009 / Many roads to maturity: microRNA biogenesis pathways and their regulation / Nat. Cell Biol 11:228~234
Yoo CB / 2006 / Epigenetic therapy of cancer: past, present and future / Nat. Rev. Drug Discov 5:37~50
Li Y / 2010 / Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research / Pharm. Res 27:1027~1041
Li Y / 2010 / Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components / Curr. Med. Chem 17:2141~2151
Winter J / 2009 / Many roads to maturity: microRNA biogenesis pathways and their regulation / Nat. Cell Biol 11:228~234
Yoo CB / 2006 / Epigenetic therapy of cancer: past, present and future / Nat. Rev. Drug Discov 5:37~50
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UCI(KEPA) : I410-ECN-0101-2017-594-002253294