지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.12
- 수록면
- 193 - 199 (7page)
이용수
초록· 키워드
오류제보하기
Global warming caused from the heavy consumption of fossil fuel is one of the biggest problems to be solved. Biofuel has been gained more attention as an alternative to reduce the consumption of fossil fuel. Recently, butanol produced from the genus Clostridium has been considered as one of the promising alternatives for gasoline, fossil based fuel. Nevertheless, the lack of the genome-engineering tools for the genus Clostridium is the major hurdle for the economic production of butanol. More recently, genome engineering tools have been developed for metabolic engineering of butanolproducing Clostridium species, which includes genome scale network model and genome editing tools on the basis of mobile group II introns and CRISPR/Cas system. In this study, the genome engineering tools for butanol-producing Clostridium species have been reviewed with a brief future perspective.
목차
Abstract
1. INTRODUCTION
2. Butanol 생산용 Clostridium 속 미생물 게놈 정보 및 in silico 모델의 개발
3. Mobile group Ⅱ intron을 이용한 butanol 생합성 Clostridium 속 미생물 게놈 편집
4. CRISPR/Cas9을 이용한 butanol 생합성 Clostridium 속 미생물의 게놈 편집
5. CONCLUSION
REFERENCES
참고문헌 (46)
참고문헌 신청
Jang, Y. S. / 2012 / Enhanced butanol production obtained by reinforcing the direct butanol-forming route in Clostridium acetobutylicum / mBio 3:e00314-12
Nolling, J. / 2001 / Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum / J. Bacteriol 183:4823~4838
Cho, C. / 2015 / Metabolic engineering of clostridia for the production of chemicals / Biof. Bioprod. Bioref 9:211~225
Mo, X. / 2015 / Genome sequence of Clostridium acetobutylicum GX AS18-1, a novel biobutanol production strain / Genome Announc 3:e00033-15
Bao, G. / 2011 / Complete genome sequence of Clostridium acetobutylicum DSM 1731, a solvent-producing strain with multireplicon genome architecture / J. Bacteriol 193:5007~5008
Nolling, J. / 2001 / Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum / J. Bacteriol 183:4823~4838
Cho, C. / 2015 / Metabolic engineering of clostridia for the production of chemicals / Biof. Bioprod. Bioref 9:211~225
Mo, X. / 2015 / Genome sequence of Clostridium acetobutylicum GX AS18-1, a novel biobutanol production strain / Genome Announc 3:e00033-15
Bao, G. / 2011 / Complete genome sequence of Clostridium acetobutylicum DSM 1731, a solvent-producing strain with multireplicon genome architecture / J. Bacteriol 193:5007~5008
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UCI(KEPA) : I410-ECN-0101-2017-470-001981521