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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 환경독성보건학회 Environmental Analysis Health and Toxicology Environmental Health and Toxicology Vol.30
- 발행연도
- 2015.12
- 수록면
- 131 - 136 (6page)
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초록· 키워드
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Objectives: In this study, the possibility of using existing test data provided in Korea and elsewhere for the registration of chemical substances was examined. Data on 510 chemical substances that are among the first subject to registration under the “Act on the Registration and Evaluation, etc. of Chemical Substances (K-REACH)” were analyzed.
Methods: The possibility of using existing data from 16 reference databases was examined for 510 chemical substances notified in July 2015 as being subject to registration.
Results: Test data with the reliability required for the registration of chemical substances under the K-REACH constituted 48.4% of the required physicochemical characteristics, 6.5% of the required health hazards, and 9.4% of the required environmental hazards.
Conclusions: Some existing test data were not within the scope of this research, including data used for registration in the European Union (EU). Thus, considering that 350 of these 510 species are registered in EU Registration, Evaluation, Authorisation & Restriction of Chemicals, more test data may exist that can be utilized in addition to the data identified in this study. Furthermore, the K-REACH states that non-testing data (test results predicted through Read Across, Quantitative Structure- Activity Relationships) and the weight of evidence (test results predicted based on test data with low reliability) can also be utilized for registration data. Therefore, if methods for using such data were actively reviewed, it would be possible to reduce the cost of securing test data required for the registration of chemical substances.
Methods: The possibility of using existing data from 16 reference databases was examined for 510 chemical substances notified in July 2015 as being subject to registration.
Results: Test data with the reliability required for the registration of chemical substances under the K-REACH constituted 48.4% of the required physicochemical characteristics, 6.5% of the required health hazards, and 9.4% of the required environmental hazards.
Conclusions: Some existing test data were not within the scope of this research, including data used for registration in the European Union (EU). Thus, considering that 350 of these 510 species are registered in EU Registration, Evaluation, Authorisation & Restriction of Chemicals, more test data may exist that can be utilized in addition to the data identified in this study. Furthermore, the K-REACH states that non-testing data (test results predicted through Read Across, Quantitative Structure- Activity Relationships) and the weight of evidence (test results predicted based on test data with low reliability) can also be utilized for registration data. Therefore, if methods for using such data were actively reviewed, it would be possible to reduce the cost of securing test data required for the registration of chemical substances.
목차
Introduction
Materials and Methods
Results
Discussion
References
참고문헌 (6)
참고문헌 신청
Korea Ministry of Government Legislation / Act on the Registration and Evaluation, etc. of Chemical Substances, Article 10;2015Jan 1
Korea Ministry of Government Legislation / Enforcement Rule of the Act on the Registration and Evaluation, etc. of Chemical Substances, Article 5; 2015 Oct 30
Lee JB. / 2012 / Cost-benefit analysis in accordance with pre-legislation registration and evaluation of chemicals: focused on direct costs
Na SH / 2014 / Survey and analysis report on the business of research and development of Gwangju in 2013 :75
Korea Ministry of Government Legislation / Enforcement Decree of the Act on the Registration and Evaluation, etc. of Chemical Substances, Article 13; 2015 Jan 1
Korea Ministry of Government Legislation / Enforcement Rule of the Act on the Registration and Evaluation, etc. of Chemical Substances, Article 5; 2015 Oct 30
Lee JB. / 2012 / Cost-benefit analysis in accordance with pre-legislation registration and evaluation of chemicals: focused on direct costs
Na SH / 2014 / Survey and analysis report on the business of research and development of Gwangju in 2013 :75
Korea Ministry of Government Legislation / Enforcement Decree of the Act on the Registration and Evaluation, etc. of Chemical Substances, Article 13; 2015 Jan 1
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UCI(KEPA) : I410-ECN-0101-2017-539-000798953