지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.89 No.4
- 발행연도
- 2015.9
- 수록면
- 167 - 175 (9page)
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초록· 키워드
오류제보하기
Purpose: Pancreatic body/tail cancer often involves the celiac axis (CA) and it is regarded as an unresectable disease. To treat the disease, we employed distal pancreatectomy with en bloc celiac axis resection (DP-CAR) and reviewed our experiences.
Methods: We performed DP-CAR for seven patients with pancreatic body/tail cancer involving the CA. The indications of DP-CAR initially included tumors with definite invasion of CA and were later expanded to include borderline resectable disease. To determine the efficacy of DP-CAR, the clinico-pathological data of patients who underwent DP-CAR were compared to both distal pancreatectomy (DP) group and no resection (NR) group.
Results: The R0 resection rate was 71.4% and was not statistically different compared to DP group. The operative time (P = 0.018) and length of hospital stay (P = 0.022) were significantly longer in DP-CAR group but no significant difference was found in incidence of the postoperative pancreatic fistula compared to DP group. In DP-CAR group, focal hepatic infarction and transient hepatopathy occurred in 1 patient and 3 patients, respectively. No mortality occurred in DP-CAR group. The median survival time (MST) was not statistically different compared to DP group. However, the MST of DP-CAR group was significantly longer than that of NR group (P < 0.001).
Conclusion: In our experience, DP-CAR was safe and offered high R0 resection rate for patients with pancreatic body/tail cancer with involvement of CA. The effect on survival of DP-CAR is comparable to DP and better than that of NR. However, the benefits need to be verified by further studies in the future.
Methods: We performed DP-CAR for seven patients with pancreatic body/tail cancer involving the CA. The indications of DP-CAR initially included tumors with definite invasion of CA and were later expanded to include borderline resectable disease. To determine the efficacy of DP-CAR, the clinico-pathological data of patients who underwent DP-CAR were compared to both distal pancreatectomy (DP) group and no resection (NR) group.
Results: The R0 resection rate was 71.4% and was not statistically different compared to DP group. The operative time (P = 0.018) and length of hospital stay (P = 0.022) were significantly longer in DP-CAR group but no significant difference was found in incidence of the postoperative pancreatic fistula compared to DP group. In DP-CAR group, focal hepatic infarction and transient hepatopathy occurred in 1 patient and 3 patients, respectively. No mortality occurred in DP-CAR group. The median survival time (MST) was not statistically different compared to DP group. However, the MST of DP-CAR group was significantly longer than that of NR group (P < 0.001).
Conclusion: In our experience, DP-CAR was safe and offered high R0 resection rate for patients with pancreatic body/tail cancer with involvement of CA. The effect on survival of DP-CAR is comparable to DP and better than that of NR. However, the benefits need to be verified by further studies in the future.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (18)
참고문헌 신청
[학술지(정기간행물)] - Varadhachary GR. / 2006 / Borderline resectable pancreatic cancer : definitions, management, and role of preoperative therapy / Ann Surg Oncol 13 : 1035 ~ 1046
[학술지(정기간행물)] - Ravikumar R. / 2014 / Portal vein resection in borderline resectable pancreatic cancer : a United Kingdom multicenter study / J Am Coll Surg 218 : 401 ~ 411
[학술지(정기간행물)] - Sperti C. / 2010 / Distal pancreatectomy for body-tail pancreatic cancer : is there a role for celiac axis resection? / Pancreatology 10 : 491 ~ 498
[학술지(정기간행물)] - Bockhorn M. / 2014 / Borderline resectable pancreatic cancer : a consensus statement by the International Study Group of Pancreatic Surgery(ISGPS) / Surgery 155 : 977 ~ 988
[학술지(정기간행물)] - Bassi C. / 2005 / Postoperative pancreatic fistula : an international study group(ISGPF)definition / Surgery 138 : 8 ~ 13
[학술지(정기간행물)] - Ravikumar R. / 2014 / Portal vein resection in borderline resectable pancreatic cancer : a United Kingdom multicenter study / J Am Coll Surg 218 : 401 ~ 411
[학술지(정기간행물)] - Sperti C. / 2010 / Distal pancreatectomy for body-tail pancreatic cancer : is there a role for celiac axis resection? / Pancreatology 10 : 491 ~ 498
[학술지(정기간행물)] - Bockhorn M. / 2014 / Borderline resectable pancreatic cancer : a consensus statement by the International Study Group of Pancreatic Surgery(ISGPS) / Surgery 155 : 977 ~ 988
[학술지(정기간행물)] - Bassi C. / 2005 / Postoperative pancreatic fistula : an international study group(ISGPF)definition / Surgery 138 : 8 ~ 13
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UCI(KEPA) : I410-ECN-0101-2016-514-002004097