지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.4
- 수록면
- 64 - 74 (11page)
이용수
초록· 키워드
오류제보하기
The present study was undertaken to examine the immunological effects of pentabrominated diphenyl ether (penta-BDE) and decabrominated diphenyl ether (deca-BDE) on the immune system of the dams and the developmental immune system of the offsprings. Methods: In this study, mated female C57BL/6J mice were orally administered penta-BDE, deca-BDE or corn oil for 5 weeks, from gestational day 6 to lactational day 21. Results: The body weight of PND21 exposed to penta-BDE was significantly decreased relative to control mice, but that of post-natal day 63 (PND63) were recovered. Orally dosed dams with penta-BDE had significantly smaller absolute and relative spleen masses than control mice. Absolute and relative spleen and thymus masses of PND21 exposed to penta-BDE were significantly decreased over control. The exposure of dams and PND21 with penta-BDE reduced the number of splenocytes and thymocytes. As results of hematologic analysis, percentage WBC and percentage neutrophils increased in dams with deca-BDE. Splenic T cell proliferation in dams and PND21 exposed to penta-BDE was increased, and there were no significant difference in splenic B cell proliferation in all treatment groups. As results of flow cytometric analysis of splenocyte, percentage total T cell, Th cell and Tc cell in PND21 exposed to penta-BDE was slightly increased, and percentage macrophage in dams and PND21 exposed to deca-BDE was decreased. The ELISA results of antibody production show no significant difference in all treatment groups relative to controls. Conclusion: These results imply that PBDEs given to the dam were transferred to the offspring during gestation and lactation, and PBDEs transferred from the dam affect immune system of offspring.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
안성 지역 소나무 잎과 토양 중 PBDEs의 농도 수준 및 특성
한국환경보건학회지
2006 .01
-
토양 중 PBDEs와 PCBs의 농도분포
한국환경보건학회지
2009 .01
-
서울 거주 산모 모유 중 PBDEs 이성질체 농도 및 노출 요인에 관한 연구
한국환경보건학회지
2011 .01
-
Method for quick identification and separation of BDE-47 by using single-stranded nucleic acid aptamers specifically binding to PBDEs
환경독성보건학회 심포지엄 및 학술대회
2015 .10
-
Occurrences of several polybrominated diphenyl ethers (PBDEs) in maternal and matching cord blood serum in South Korea
환경독성보건학회 심포지엄 및 학술대회
2013 .10
-
Immunotoxicity Following Pre- and Post-natal Aluminum Exposure in Rats
Toxicological Research
2008 .03
-
In Utero Exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Affects the Development of Reproductive System in Mouse
Yonsei Medical Journal
2008 .01
-
Downregulation of Peritoneal Macrophage Activity in Mice Exposed to Bisphenol A During Pregnancy and Lactation
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2007 .01
-
Assessing risk of substitution with the example of deca brominated diphenyl ether in Japan
환경독성보건학회 심포지엄 및 학술대회
2004 .11
-
오배자 BuOH층에서 분리한 1,2,3,4,6-penta-O-galloyl-β-Dglucose의 세포간교통 회복 및 혈관형성 억제작용에 대한 효과
동의생리병리학회지
2002 .06
-
Developmental Toxicity by Exposure to Bisphenol A Diglycidyl Ether during Gestation and Lactation Period in Sprague-dawley Male Rats
예방의학회지
2007 .01
-
Effects of early prepubertal exposure to bisphenol A on the onset of puberty, ovarian weights, and estrous cycle in female mice
Clinical and experimental reproductive medicine : CERM
2011 .01
-
Inhibition of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 Activity by $1,2,3,4,6-Penta-Ο-galloyl-{\beta}-D-glucose$ in Murine Macrophage Cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2003 .01
-
Bisphenol A-induced overall immune downregulation in mice
대한약학회 학술대회
2003 .01
-
새로운 안트라사이클린계 항암제 DA-125의 생식독성연구: (I) 랫트 최기형시험
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
1994 .01
-
Effects of Acanthopanax sessiliflorus on Immune Cells such as Thymocytes, Splenocytes and Macrophages in Mice
대한한방내과학회지
2007 .01
-
Water treatment technologies for efficient removal of polybrominated diphenyl ethers (PBDEs) - A review
환경독성보건학회 심포지엄 및 학술대회
2019 .04
-
새로운 관절염 CONP01의 생식독성연구: 랫드 배·태자 발생시험
Toxicological Research
2005 .03
-
감마선에 조사된 생쥐에 있어서 방사선방어효과 평가를 위한 생물학적 파라메타
약학회지
1999 .01
-
임신중인 생쥐에 Bisphenol A 투여가 모체의 생식독성과 태아의 성비에 미치는 영향
Toxicological Research
2005 .06
이 논문의 저자 정보
이 논문과 함께 이용한 논문
Study on distribution characteristics of brominated flame retardants (HBCD, PBDEs) in ambient and soil
Ho-Joong Kim
,
Chan-Yoon Jeong
,
Hwan-Sup Lee
외 6명
환경독성보건학회 심포지엄 및 학술대회
2019
.04
Distribution of brominated flame retardants and phthalate esters in house dust in Korea
Deok-Jun Kweon
,
Moon-Kyung Kim
,
Kyung-Duk Zoh
Environmental Engineering Research
2018
.12
Potential Health Risks from Persistent Organic Pollutants (POPs) in Marine Ecosystem
Youn Ju Lee
,
Jae-Seok Jang
,
Jae-Ho Yang
한국해양바이오학회지
2016
.06
Bioaccumulation and time trends of brominated flame retardants in marine mammals from Korean coastal waters
조영은
,
정윤선
,
문효방
환경독성보건학회 심포지엄 및 학술대회
2019
.10
Multimatrix distribution and bioaccumulation of hexabromocyclododecanes (HBCDDs) in environment of Korea
조영은
,
이현경
,
이재우
외 2명
환경독성보건학회 심포지엄 및 학술대회
2019
.10
최근 본 자료
댓글(0)
0