지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 440 - 449 (10page)
이용수
초록· 키워드
오류제보하기
Objectives: This study was designed to determine the levels of polybrominated diphenyl ethers (PBDEs) in breast milk and to evaluate the relations with factors affecting these levels.
Methods: The congener levels of PBDE in 22 samples of breast milk were analyzed using a high resolution gas chromatograph with a high resolution mass detector. In accordance with our standard operating procedures, the recoveries of internal standards had to range between 68% and 118%. Since the distribution of PBDE concentrations is close to log-normal, the data were logarithmically transformed before analysis. Test subjects were healthy primipara and multipara mothers with a mean age of 32 (SD = 2.7) in 2006.
Results: Seven PBDE congeners (BDE-28, 47, 99, 100, 153, 154, and 183) were detected and identified in all of the pooled breast milk samples, indicating widespread contamination from PBDEs in the environment in Korea. Residue levels of total PBDEs (sum PBDEs from tri- to hepta-BDE) ranged from 0.84-13.1 ng/g lipid with median and geometric mean levels of 2.6 ng/g lipid and 2.74 ng/g lipid, respectively. PBDE congeners 47, 99 and 153 markedly predominated and accounted for about 75% of the amount of the PBDE congeners analyzed. BDE-47 was the dominant congener in most samples, whereas BDE-153 was predominant in a few (n = 7/22). BDE-47 was highly correlated with total PBDEs (r = 0.987, p < 0.01). In analyses of the differences of the means of log transformed breast milk PBDE levels for groups of potential covariates, only breast milk BDE-47 and BDE-99 levels were significantly associated with fish (p < 0.05) and meat consumption (p < 0.01). However, we did not find significant correlations between PBDE levels and maternal age, body mass index (BMI), parity, job presence and smoking status.
Conclusions: Our findings are mainly limited due to the small sampling size and low doses of PBDEs exposure.
Background and human exposure data of PBDEs is lacking, and longitudinal investigations into the environment and biota are encouraged to determine the health impact on future populations in Korea.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Bromine Science and Environmental Forum / / Bromine Science and Environmental Forum
Darnerud PO / 2006 / Dietary intake estimations of organohalogen contaminants (dioxins, PCB, PBDE and chlorinated pesticides, e.g. DDT) based on Swedish market basket data /
Jones-Otazo HA / 2005 / Is house dust the missing exposure pathway for PBDEs? An analysis of the urban fate and human exposure to PBDEs / Environ Sci Technol 39 : 5121 ~ 5230
KEI / 2001 / Environmental risk assessment and regulation on flame retardants
Kunisue T / 2007 / Polybrominated diphenyl ethers and persistent organochlorines in Japanese human adipose tissues / Environ Int 33 : 1048 ~ 1056
Darnerud PO / 2006 / Dietary intake estimations of organohalogen contaminants (dioxins, PCB, PBDE and chlorinated pesticides, e.g. DDT) based on Swedish market basket data /
Jones-Otazo HA / 2005 / Is house dust the missing exposure pathway for PBDEs? An analysis of the urban fate and human exposure to PBDEs / Environ Sci Technol 39 : 5121 ~ 5230
KEI / 2001 / Environmental risk assessment and regulation on flame retardants
Kunisue T / 2007 / Polybrominated diphenyl ethers and persistent organochlorines in Japanese human adipose tissues / Environ Int 33 : 1048 ~ 1056
이 논문의 저자 정보
최근 본 자료
댓글(0)
0