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학술저널
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대한바이러스학회 JOURNAL OF BACTERIOLOGY AND VIROLOGY 大韓바이러스學會誌 제18권 제2호
발행연도
1988.12
수록면
181 - 188 (8page)

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Serovirological study on HIV infection among Korean in Korea was performed for the clarification of HIV transmission modes in Korea and for the isolation of HIV from infected persons. Big differences of specificities among test methods for HIV antibody detection were found. Indirect Enzyme Linked Immunosorbent Assay(ELISA) showed lower specificities, whereas Particle Agglutination(PA), competitive inhibition ELISA, Western Blot(WB) and Immunofluorescence Antibody(IFA) test showed higher specificities. IFA showed lower sensitivities even though the exact evaluation of sensitivity on HIV infection is difficult. 32 HIV infected persons including 4 Acquired Immunodeficiency Syndrome(AIDS) case were detected from the serum specimens more than one million tested. Prostitutes to foreigners and sailors overseas had highest infection rate compared with other occupational group. HIV infected persons from hemophiliacs and drug abusers were very rare to the contrary with those of other countries. Nurnbers of infected persons were 2 to 3 times more than those of the previous years, Sex ratio of male to female was 1.3 to 1. More male infected persons were detected from 1988. HIV was isolated from 2 persons out of 24 infected persons tested. All of persons who secret HIV were in the last stage of AIDS. HIV antigen was demonstrated from HIV infected person without virus secretions.

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