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자료유형
학술저널
저자정보
Sung-Myung Kang (Jeju National University) Seung-Hong Lee (Jeju National University) Soo-Jin Heo (Korea Ocean Research and Development Institute) Kil-Nam Kim (Korea Basic Science Institute) You-Jin Jeon (Jeju National University)
저널정보
대한지역사회영양학회 Nutrition Research and Practice Nutrition Research and Practice Vol.5 No.6
발행연도
2011.12
수록면
495 - 502 (8page)

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In this study, antioxidant and free radical scavenging activities of the natural antioxidative compound, pyrogallol-phloroglucinol-6,6"-bieckol (PPB) isolated from brown algae, Ecklonia cava was assessed in vitro by measuring the radical scavenging activities (DPPH, alkyl, hydroxyl, and superoxide) using electron spin resonance (ESR) spectrometry, intracellular reactive oxygen species (ROS) scavenging activity, and DNA damage assay. According to the results of these experiments, the scavenging activity PPB against difference radicals was in the following order: DPPH, alkyl, hydroxyl, and superoxide radicals (IC50 0.90, 2.54, 62.93 and 109.05 μM). The antioxidant activities of PPB were higher than that of the commercial antioxidant, ascorbic acid. Furthermore, PPB effectively inhibited DNA damage induced by H<SUB>2</SUB>O<SUB>2</SUB>. These results suggest that the natural antioxidative compound, PPB, can be used by the natural food industry.

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Abstract
Introduction
Materials and Methods
Results
Discussion
References

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