지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
A rapid, sensitive and specific method was developed and validated using electrospray ionization (ESI) tandem mass spectrometry (LC-MS/MS) for determination of misoprostol acid in human plasma. Misoprostol acid-d5 was used as in internal standard (IS). The analyte and IS were extracted by simple one step solid phase extraction (SPE). Linearity in plasma was obtained over the concentration range 10~3000 pg/mL and lower limit of quantification (LLOQ) was identifiable and reproducible at 10 pg/mL. The intra- and inter-day precision values were below 9% and the accuracy was ranged from 93.81% to 102.02% at all four quality control samples. The method was has been successfully applied for routine assay to support pharmacokinetic study of misoprostol acid in human plasma after an oral administration of 0.4 mg misoprostol.
목차
Abstract
1. Introduction
2. Experimental
3. Results and Discussion
4. Conclusions
References
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
A Sensitive and Rapid LC-MS/MS Method for Determination of Berberine in Human Plasma
Mass Spectrometry Letters
2019 .06
-
Simple and sensitive assay for quantification of oseltamivir phosphate(TamifluⓇ) in human plasma using by LC-MS/MS : Application in bioequivalence study
한국분석과학회 학술대회
2017 .11
-
Determination of clarithromycin in human plasma by LC-MS/MS : Validation and application in pharmacokinetic study
한국분석과학회 학술대회
2016 .05
-
A sensitive and rapid LC-MS method for determination of berberine in human plasma
한국분석과학회 학술대회
2019 .05
-
Determination of Paclitaxel in human plasma by LC-MS/MS method
한국분석과학회 학술대회
2023 .05
-
Determination of Risperidone in Human plasma by LC-MS/MS and its Application to a Bioequivalence Study
한국분석과학회 학술대회
2015 .11
-
Determination of Carbamazepine in human plasma by LC-MS/MS method
한국분석과학회 학술대회
2023 .05
-
A novel normal-phase LC-MS/MS method for quantitative analysis of 23 amino acids without derivatization in human plasma
한국분석과학회 학술대회
2016 .05
-
낮은 GWP를 가진 CxF2xO 을 이용한 SiO2 식각 공정 특성에 관한 연구
한국진공학회 학술발표회초록집
2020 .02
-
Simultaneous Liquid Chromatography Tandem Mass Spectrometric Determination of 35 Prohibited Substances in Equine Plasma for Doping Control
Mass Spectrometry Letters
2022 .12
-
Determination of Telmisartan in Human Plasma by LC-MS/MS Method
한국분석과학회 학술대회
2023 .05
-
A simple, rapid and sensitive for quantification of Dienogest in healthy Korean women plasma using by LC-MS/MS : Application in Bioequivalence Study
한국분석과학회 학술대회
2018 .05
-
Development of analytical method by LC-MS/MS for the quantification of salvianolic acid B in rat plasma
한국분석과학회 학술대회
2015 .11
-
Development and validation of LC-MS/MS method for the simultaneous determination of Midazolam and its metabolites in human plasma
한국분석과학회 학술대회
2023 .05
-
Plasma Properties Data Center Activities for Plasma Application in the National Fusion Research Institute
한국진공학회 학술발표회초록집
2019 .08
-
Simultaneous Determination of Irinotecan and SN-38 in human plasma by LC-MS/MS method
한국분석과학회 학술대회
2023 .05
-
Effect of hybrid plasma source on O radical generation in oxygen plasma
한국진공학회 학술발표회초록집
2018 .08
-
Plasma metabolomics study of amino acids in mice with lipopolysaccharide-Induced sepsis by LC-MS/MS
한국분석과학회 학술대회
2024 .11
-
Plasma-induced reaction at plasma-liquid and plasma-polymeric film interface by AC-driven atmospheric pressure plasma
한국진공학회 학술발표회초록집
2019 .08
-
Flexible Plasma Sheets
Applied Science and Convergence Technology
2018 .03
이 논문과 함께 이용한 논문
Development of Bio-analytical Method Validation of Montelukast by LC-MS-MS
Hye Jin Kim
,
Sun Koung Joung
,
Kyung Hee Cho
외 2명
한국분석과학회 학술대회
2010
.05
Validated LC-MS/MS Method for Determination of Amlodipine in Human Plasma
Jae Woo Song
,
Sun Koung Joung
,
Kyung Hee Cho
외 2명
한국분석과학회 학술대회
2009
.05
고체상추출과 GC/MS를 이용한 소변 중 암페타민계 마약성분 동시분석법
정재철
,
김진영
,
인문교
외 1명
분석과학
2008
.02
LC-MS/MS를 이용한 혈장 중 레르카니디핀의 분석
장문선
,
나숙희
,
장규영
외 4명
분석과학
2008
.02
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2016-433-001262415