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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.9
- 수록면
- 131 - 135 (5page)
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Helicobacter pylori-eliminating effects of FEMY-R7, composed of fucoidan and evening primrose extract, were investigated in mice and humans. Male C57BL/6 mice were infected with the bacteria by intragastric inoculation (1×10<SUP>9</SUP> CFU/mouse) 3 times at 2-day intervals, and simultaneously, orally treated twice a day with 10 or 100 mg/kg FEMY-R7 for 2 weeks. In Campylobcter-like organism-detection test, FEMY-R7 markedly reduced the urease-positive reactivity. In a clinical sudy, human subjects, confirmed to be infected with Helicobacter pylori, were orally administered twice a day with a capsule containing 150 mg FEMY-R7 for 8 weeks. FEMY-R7 significantly decreased both the Delta over baseline-value in urea breath test and the serum pepsinogens I and II levels. The results indicate that FEMY-R7 not only eliminates H. pylori from gastric mucosa of animals and humans, but also improves gastric function.
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참고문헌 (48)
참고문헌 신청
1. [학술지(정기간행물)] - Wallace JL. / 1996 / The cellular and molecular basis of gastric mucosal defense / FASEB J 10 (7) : 731 ~ 740
2. [단행본] - Neal MJ. / 2003 / Medical Pharmacology at a Glance. 3rd ed / Blackwell Publishing Inc : 30 ~ 31
3. [학술지(정기간행물)] - Isobe H. / 2004 / Activated protein C reduces stress-induced gastric mucosal injury in rats by inhibiting the endothelial cell injury / J Thromb Haemost 2 (2) : 313 ~ 320
4. [학술지(정기간행물)] - 김윤배 / 2007 / The Role of Corticosteroids in Stress-Induced Gastric Ulceration in Rats / Laboratory Animal Research 23 (2) : 127 ~ 131
5. [학술지(정기간행물)] - Slomiany BL. / 1997 / Induction of tumor necrosis factor-alpha and apoptosis in gastric mucosal injury by indomethacin : effect of omeprazole and ebrotidine / Scand J Gastroenterol 32 (7) : 638 ~ 642
2. [단행본] - Neal MJ. / 2003 / Medical Pharmacology at a Glance. 3rd ed / Blackwell Publishing Inc : 30 ~ 31
3. [학술지(정기간행물)] - Isobe H. / 2004 / Activated protein C reduces stress-induced gastric mucosal injury in rats by inhibiting the endothelial cell injury / J Thromb Haemost 2 (2) : 313 ~ 320
4. [학술지(정기간행물)] - 김윤배 / 2007 / The Role of Corticosteroids in Stress-Induced Gastric Ulceration in Rats / Laboratory Animal Research 23 (2) : 127 ~ 131
5. [학술지(정기간행물)] - Slomiany BL. / 1997 / Induction of tumor necrosis factor-alpha and apoptosis in gastric mucosal injury by indomethacin : effect of omeprazole and ebrotidine / Scand J Gastroenterol 32 (7) : 638 ~ 642
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UCI(KEPA) : I410-ECN-0101-2015-500-002710887