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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 47 - 51 (5page)
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초록· 키워드
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The transformation of ginsenoside Rb1 into a specific minor ginsenoside using Aspergillus niger KCCM 11239, as well as the identification of the transformed products and the pathway via thin layer chromatography and high performance liquid chromatography were evaluated to develop a new biologically active material. The conversion of ginsenoside Rb1 generated Rd, Rg3, Rh2, and compound K although the reaction rates were low due to the low concentration. In enzymatic conversion, all of the ginsenoside Rb1 was converted to ginsenoside Rd and ginsenoside Rg3 after 24 h of incubation. The crude enzyme (β-glucosidase) from A. niger KCCM 11239 hydrolyzed the β-(1→6)-glucosidic linkage at the C-20 of ginsenoside Rb1 to generate ginsenoside Rd and ginsenoside Rg3. Our experimental demonstration showing that A. niger KCCM 11239 produces the ginsenoside-hydrolyzing β-glucosidase reflects the feasibility of developing a specific bioconversion process to obtain active minor ginsenosides.
목차
ABSTRACT
1. Introduction
2. Materials and methods
3. Results
References
참고문헌 (31)
참고문헌 신청
1. [학술지(정기간행물)] - Baque MA / 2012 / Production of biomass and useful compounds from adventitious roots of high-value added medicinal plants using bioreactor / Biotechnol Adv 30 : 1255 ~ 1267
2. [학술지(정기간행물)] - Seungheon Han / 2012 / Effects of Ginsenoside on Pacemaker Potentials of Cultured Interstitial Cells of Cajal Clusters from the Small Intestine of Mice / Molecules and Cells 33 (3) : 243 ~ 249
3. [학술지(정기간행물)] - Shibata S / 1966 / Chemical Studies on the Oriental Plant Drugs. XVII. The prosapogenin of the ginseng saponins: ginsenosides-Rb1,-Rb2, and-Rc / Chem Pharm Bull 14 : 1157 ~ 1161
4. [학술지(정기간행물)] - Cheng LQ / 2008 / Conversion of major ginsenoside Rb1 to 20(S)-ginsenoside Rg3 by Microbacterium sp. GS514 / Phytochemistry 69 : 218 ~ 224
5. [학술지(정기간행물)] - Li WK / 2000 / Use of high performance liquid chromatography tandem mass spectrometry to distinguish Panax ginseng C.A. Meyer (Asian ginseng) and Panax quinquefolius. L. (American ginseng) / Anal Chem 72 : 5417 ~ 5422
2. [학술지(정기간행물)] - Seungheon Han / 2012 / Effects of Ginsenoside on Pacemaker Potentials of Cultured Interstitial Cells of Cajal Clusters from the Small Intestine of Mice / Molecules and Cells 33 (3) : 243 ~ 249
3. [학술지(정기간행물)] - Shibata S / 1966 / Chemical Studies on the Oriental Plant Drugs. XVII. The prosapogenin of the ginseng saponins: ginsenosides-Rb1,-Rb2, and-Rc / Chem Pharm Bull 14 : 1157 ~ 1161
4. [학술지(정기간행물)] - Cheng LQ / 2008 / Conversion of major ginsenoside Rb1 to 20(S)-ginsenoside Rg3 by Microbacterium sp. GS514 / Phytochemistry 69 : 218 ~ 224
5. [학술지(정기간행물)] - Li WK / 2000 / Use of high performance liquid chromatography tandem mass spectrometry to distinguish Panax ginseng C.A. Meyer (Asian ginseng) and Panax quinquefolius. L. (American ginseng) / Anal Chem 72 : 5417 ~ 5422
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UCI(KEPA) : I410-ECN-0101-2015-520-001297385