지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.10
- 수록면
- 433 - 438 (6page)
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초록· 키워드
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These studies were conducted to investigate the alcohol degradation effects of the extract of herbal composition (DTS20) containing Viscum album L., Lycium chinense L., Inonotus obliquus and Acanthopanax senticosus H., on the alcohol administered mice. To investigate anti-hangover effect, alcohol and alcohol dehydrogensae (ADH) concentration of blood were measured after oral administration of ethanol. The administration of DTS20 (200-500 mg/kg) had beneficial actions toward alcohol degradation in acute alcohol treated mice model. The oral administration of DTS20 showed decreased gastric mucous membrane damage produced in ethanol treated mice. In addition, intraperitoneal administration of DTS20 showed anti-inflammatory effects in inhibition tests of vascular permeability produced by acetic acid. DTS20 also reduced the concentration of nitric oxide (NO), tumor necrosis factor (TNF)-α in macrophages that were activated by LPS. These results demonstrate that DTS20 possesses potential to stimulate the alcohol degradation and inhibit the inflammatory effects in mice.
목차
Abstract
1. 서론
2. 재료 및 방법
3. 결과 및 고찰
4. 결론
References
참고문헌 (28)
참고문헌 신청
2. [학술지(정기간행물)] - Wang, X / 2010 / The protective effects of Acanthopanax senticosus Harms aqueous extracts against oxidative stress: role of Nrf2 and antioxidant enzymes / J. Ethnopharmacol 127 : 424 ~ 432
3. [학술지(정기간행물)] - Day, C. P / 2006 / Genes or environment to determine alcoholic liver disease and non-alcoholic fatty liver disease / Liver Int 26 : 1021 ~ 1028
4. [학술지(정기간행물)] - Mansouri, A. / 2001 / Acute ethanol administration oxidatively damages and depletes mitochondrial DNA in mouse liver, brain, heart, and skeletal muscles: protective effects of antioxidants / J. Pharmacol. Exp. Ther 298 : 737 ~ 743
5. [학술지(정기간행물)] - Thurman, R. G. / 1997 / Role of kuffer cells, endotoxin and free radicals in hepatotoxicity due to prolonged alcohol consumption: studies in female and male rats / J. Nutr 127 : 903 ~ 906
6. [학술지(정기간행물)] - Albano, E / 2008 / Oxidative mechanisms in the pathogenesis of alcoholic liver disease / Mol. Aspects Med 29 : 9 ~ 16
3. [학술지(정기간행물)] - Day, C. P / 2006 / Genes or environment to determine alcoholic liver disease and non-alcoholic fatty liver disease / Liver Int 26 : 1021 ~ 1028
4. [학술지(정기간행물)] - Mansouri, A. / 2001 / Acute ethanol administration oxidatively damages and depletes mitochondrial DNA in mouse liver, brain, heart, and skeletal muscles: protective effects of antioxidants / J. Pharmacol. Exp. Ther 298 : 737 ~ 743
5. [학술지(정기간행물)] - Thurman, R. G. / 1997 / Role of kuffer cells, endotoxin and free radicals in hepatotoxicity due to prolonged alcohol consumption: studies in female and male rats / J. Nutr 127 : 903 ~ 906
6. [학술지(정기간행물)] - Albano, E / 2008 / Oxidative mechanisms in the pathogenesis of alcoholic liver disease / Mol. Aspects Med 29 : 9 ~ 16
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UCI(KEPA) : I410-ECN-0101-2014-400-002405599