지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.6
- 수록면
- 196 - 201 (6page)
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초록· 키워드
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Silkworm-derived silk materials which contain 45 to 55% protein (18 amino acids, including 8 essential amino acids) have free radical-scavenging activities. In the present study, we investigated the whitening and anti-aging effects of silkworm gland under various conditions with B16F1 melanoma cells and human dermal fibroblasts. To evaluate the toxicity of soluble gland hydrolysate (SGH), mouse-derived B16F1 melanoma cells were treated with 0.2~5 mg/mL, cytotoxicity was not observed at all concentrations. The tyrosinase and elastase activities were significantly decreased as dosage levels of SGH increased. In addition, cell death was decreased by treated with SGH and antioxidative activity was the most effective in the SGH treatment. These findings suggest that SGH may be used as a potential functional biomaterial in having the skin whitening effect and anti-aging activity by inhibition of tyrosinase and elastase activities.
목차
Abstract
1. 서론
2. 재료 및 방법
3. 결과 및 고찰
4. 결론
REFERENCES
참고문헌 (27)
참고문헌 신청
1. [학술지(정기간행물)] - Souza, P. M. / 2012 / Plants from Brazilian Cerrado with potent tyrosinase inhibitory activity / PLoS One 7 : e48589 ~
2. [학술지(정기간행물)] - Oh, H. / 2011 / Refining hot-water extracted silk sericin by ethanol-induced precipitation / Int. J. Biol. Macromol 48 : 32 ~ 37
3. [학술지(정기간행물)] - Daithankar, A. V. / 2005 / Moisturizing efficiency of silk protein hydrolysate silk fibroin / Indian J. Biotechnol 4 : 115 ~ 121
4. [학술지(정기간행물)] - 김대원 / 2011 / Effect of silk fibroin peptide derived from silkworm Bombyx mori on the anti-inflammatory effect of Tat-SOD in a mice edema model / BMB Reports 44 (12) : 787 ~ 792
5. [학술지(정기간행물)] - Kato, N. / 1998 / Silk protein, sericin, inhibits lipid peroxidation and tyrosinase activity / Biosci. Biotechnol. Biochem 62 : 145 ~ 147
2. [학술지(정기간행물)] - Oh, H. / 2011 / Refining hot-water extracted silk sericin by ethanol-induced precipitation / Int. J. Biol. Macromol 48 : 32 ~ 37
3. [학술지(정기간행물)] - Daithankar, A. V. / 2005 / Moisturizing efficiency of silk protein hydrolysate silk fibroin / Indian J. Biotechnol 4 : 115 ~ 121
4. [학술지(정기간행물)] - 김대원 / 2011 / Effect of silk fibroin peptide derived from silkworm Bombyx mori on the anti-inflammatory effect of Tat-SOD in a mice edema model / BMB Reports 44 (12) : 787 ~ 792
5. [학술지(정기간행물)] - Kato, N. / 1998 / Silk protein, sericin, inhibits lipid peroxidation and tyrosinase activity / Biosci. Biotechnol. Biochem 62 : 145 ~ 147
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UCI(KEPA) : I410-ECN-0101-2014-400-002407851