지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.6
- 수록면
- 99 - 102 (4page)
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초록· 키워드
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Serum samples, 100 in the total number, were collected from different laboratories in Tehran, Iran and tested for anti-Toxoplasma specific IgG and IgM antibodies using indirect immunofluorescent antibody test (IFAT). Using the IgG (chronic) and IgM (acute) positive samples, the IgG avidity test was performed by ELISA in duplicate rows of 96-well microtiter plates. One row was washed with 6 M urea and the other with PBS (pH 7.2), then the avidity index (AI) was calculated. Sixteen out of 18 (88.9%) sera with acute toxoplasmosis showed low avidity levels (AI≤50), and 76 out of 82 (92.7%) sera in chronic phase of infection showed high avidity index (AI>60). Six sera had borderline ranges of AI. The results showed that the IgG avidity test by ELISA could distinguish the acute and chronic stages of toxoplasmosis in humans.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (18)
참고문헌 신청
1. [학술지(정기간행물)] - Leite M / 2008 / Correlation between specific IgM levels and percentage IgG-class antibody avidity to Toxoplasma gondii / Rev Inst Med Trop Sao Paulo 50 : 237 ~ 242
2. [학술지(정기간행물)] - Iqbal J / 2007 / Detection of acute Toxoplasma gondii infection in early pregnancy by IgG avidity and PCR analysis / J Med Microbiol 56 (Pt 11) : 1495 ~ 1499
3. [학술지(정기간행물)] - Candolfi E / 2007 / IgG avidity assay firms up the diagnosis of acute toxoplasmosis on the first serum sample in immunocompetent pregnant women / Diagn Microbiol Infect Dis 58 : 83 ~ 88
4. [학술지(정기간행물)] - Crucerescu E / 2002 / Study on specific IgG avidity as a tool for recent primary Toxoplasma gondii infection diagnosis / J Prev Med 10 : 56 ~ 62
5. [학술지(정기간행물)] - Roberts A / 2001 / Multicenter evaluation of strategies for serodiagnosis of primary infection with Toxoplasma gondii / Eur J Clin Microbiol Infect Dis 20 : 467 ~ 474
2. [학술지(정기간행물)] - Iqbal J / 2007 / Detection of acute Toxoplasma gondii infection in early pregnancy by IgG avidity and PCR analysis / J Med Microbiol 56 (Pt 11) : 1495 ~ 1499
3. [학술지(정기간행물)] - Candolfi E / 2007 / IgG avidity assay firms up the diagnosis of acute toxoplasmosis on the first serum sample in immunocompetent pregnant women / Diagn Microbiol Infect Dis 58 : 83 ~ 88
4. [학술지(정기간행물)] - Crucerescu E / 2002 / Study on specific IgG avidity as a tool for recent primary Toxoplasma gondii infection diagnosis / J Prev Med 10 : 56 ~ 62
5. [학술지(정기간행물)] - Roberts A / 2001 / Multicenter evaluation of strategies for serodiagnosis of primary infection with Toxoplasma gondii / Eur J Clin Microbiol Infect Dis 20 : 467 ~ 474
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UCI(KEPA) : I410-ECN-0101-2014-510-002510801