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초록· 키워드
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Objectives: The experiment was to estimate the value of Saengmaegsan as a therapeutic anti-aging agent with an analysis of ingredients and their bio-activating effects by enzymologic methods.
Methods: We analyzed anti-aging effects of the ingredients of Saengmaegsan being Liriope Platyphylla, Schizandrae Chinensis, and Schizandrae Chinensis.
Results: In Liriope Platyphylla and Schizandrae Chinensis, reducing sugar concentration was shown at the highest level. Of mineral contents, K+ and Na+ were the highest in Saengmaegsan and each ingredient also, and then Ca++ and Al. The amount of polyphenol showed was in order Schizandrae Chinensis > Saengmaegsan > Panax Ginseng > Liriope Platyphylla. The electron donating ability of Schizandrae Chinensis doubled that of Saengmaegsan and Panax Ginseng, at the same time that one per 1 ml in Saengmaegsan was significantly found the greatest level as compared to each single ingredient. SOD-like activity was high in Saengmaegsan and Schizandrae Chinensis. SOD-like activity of Saengmaegsan was higher than in single components. Nitric oxide inhibition in pH 1.2 was high in Saengmaegsan and Schizandrae Chinensis, and for per 1 ml it showed the same pattern as above. In pH 3.0 the result was not different from in pH 1.2. Xanthine oxidase inhibition was high in Schizandrae Chinensis and for per 1 ml showed the greatest activity in Liriope Platyphylla. Tyrosinase inhibition in Omija was the most noticeable, and for per 1 ml was Liriope Platyphylla more than any others.
Conclusions: With this analysis of ingredients, it is proven that Saengmaegsan and each component fosters antioxidation. On the whole, the composite prescription Saengmaegsan was superior to each individual component.
Methods: We analyzed anti-aging effects of the ingredients of Saengmaegsan being Liriope Platyphylla, Schizandrae Chinensis, and Schizandrae Chinensis.
Results: In Liriope Platyphylla and Schizandrae Chinensis, reducing sugar concentration was shown at the highest level. Of mineral contents, K+ and Na+ were the highest in Saengmaegsan and each ingredient also, and then Ca++ and Al. The amount of polyphenol showed was in order Schizandrae Chinensis > Saengmaegsan > Panax Ginseng > Liriope Platyphylla. The electron donating ability of Schizandrae Chinensis doubled that of Saengmaegsan and Panax Ginseng, at the same time that one per 1 ml in Saengmaegsan was significantly found the greatest level as compared to each single ingredient. SOD-like activity was high in Saengmaegsan and Schizandrae Chinensis. SOD-like activity of Saengmaegsan was higher than in single components. Nitric oxide inhibition in pH 1.2 was high in Saengmaegsan and Schizandrae Chinensis, and for per 1 ml it showed the same pattern as above. In pH 3.0 the result was not different from in pH 1.2. Xanthine oxidase inhibition was high in Schizandrae Chinensis and for per 1 ml showed the greatest activity in Liriope Platyphylla. Tyrosinase inhibition in Omija was the most noticeable, and for per 1 ml was Liriope Platyphylla more than any others.
Conclusions: With this analysis of ingredients, it is proven that Saengmaegsan and each component fosters antioxidation. On the whole, the composite prescription Saengmaegsan was superior to each individual component.
목차
서론
실험
성적
고찰
결론
참고문헌
참고문헌 (37)
참고문헌 신청
1. [단행본] - 李東垣 / 1986 / 東垣十種醫書 / 五州出版社 : 19 ~
2. [단행본] - 廣州中醫學院 / 1983 / 方濟學 / 人民衛生出版社 : 245 ~ 246
3. [학술지(정기간행물)] - Shin SH / 1998 / Effects of Saengmaegsan Extract on Cultured Myocardial cells Induced by Oxygen Tension / The Journal of Korean Oriental Medicine 12 (2) : 100 ~ 111
4. [학술지(정기간행물)] - Shin SH / 1998 / Effects of Saengmaegsan Extract on Cultured Myocardial Cell Beating / The Journal of Oriental Physiology 13 (1) : 41 ~ 48
5. [학술지(정기간행물)] - Shin DC / 1999 / Effects of Saengmaegsan Extract on the Cardiovascular system and Regional Cerebral Blood flow / The Journal of Korean Oriental Internal Medicine 20 (1) : 153 ~ 166
2. [단행본] - 廣州中醫學院 / 1983 / 方濟學 / 人民衛生出版社 : 245 ~ 246
3. [학술지(정기간행물)] - Shin SH / 1998 / Effects of Saengmaegsan Extract on Cultured Myocardial cells Induced by Oxygen Tension / The Journal of Korean Oriental Medicine 12 (2) : 100 ~ 111
4. [학술지(정기간행물)] - Shin SH / 1998 / Effects of Saengmaegsan Extract on Cultured Myocardial Cell Beating / The Journal of Oriental Physiology 13 (1) : 41 ~ 48
5. [학술지(정기간행물)] - Shin DC / 1999 / Effects of Saengmaegsan Extract on the Cardiovascular system and Regional Cerebral Blood flow / The Journal of Korean Oriental Internal Medicine 20 (1) : 153 ~ 166
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UCI(KEPA) : I410-ECN-0101-2014-519-000261779