지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.6
- 수록면
- 63 - 68 (6page)
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Objectives：The purpose of this study was to examine the association of exposures to heavy metals with positive diagnosis for attention-deficit hyperactivity disorder (ADHD) and Tourette’s syndrome (TS).
Methods：Study participants included 27 children diagnosed with ADHD (9.9±2.9 years of age), 21 diagnosed with Tourette’s disorder (10.7±2.2 years of age), and 45 normal control children (9.6±0.5 years of age). A Perkin-Elmer mass spectrometer was used to measure the concentrations of 5 heavy metals (Pb, Cd, U, Be, Hg) in hair samples obtained from each participant. Each heavy metal concentration was compared among the groups by use of a Kruskal-Wallis test.
Results：The levels of lead (p=.006) and cadmium (p=.037) observed in the hair of children diagnosed with ADHD were significantly higher than those found in the control subjects. There were no significant differences observed for heavy metal levelswhen comparing TS and control subjects.
Conclusion：We confirmed that lead exposure is a risk factor for ADHD. We also identified that cadmium may be a new candidate risk factor for manifestation of ADHD. We did not find an association between heavy metals and manifestation of TS.
Methods：Study participants included 27 children diagnosed with ADHD (9.9±2.9 years of age), 21 diagnosed with Tourette’s disorder (10.7±2.2 years of age), and 45 normal control children (9.6±0.5 years of age). A Perkin-Elmer mass spectrometer was used to measure the concentrations of 5 heavy metals (Pb, Cd, U, Be, Hg) in hair samples obtained from each participant. Each heavy metal concentration was compared among the groups by use of a Kruskal-Wallis test.
Results：The levels of lead (p=.006) and cadmium (p=.037) observed in the hair of children diagnosed with ADHD were significantly higher than those found in the control subjects. There were no significant differences observed for heavy metal levelswhen comparing TS and control subjects.
Conclusion：We confirmed that lead exposure is a risk factor for ADHD. We also identified that cadmium may be a new candidate risk factor for manifestation of ADHD. We did not find an association between heavy metals and manifestation of TS.
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References
참고문헌 (44)
참고문헌 신청
1. [학술지(정기간행물)] - Cortese S / 2008 / Attention-deficit/hyperactivity disorder, Tourette’s syndrome, and restless legs syndrome: the iron hypothesis / Med Hypotheses 70 : 1128 ~ 1132
2. [학술지(정기간행물)] - Kessler RC / 2005 / Faraone SV, et al. Patterns and predictors of attention-deficit/hyperactivity disorder persistence into adulthood: results from the national comorbidity survey replication / Biol Psychiatry 57 : 1442 ~ 1451
3. [학술지(정기간행물)] - 유연아 / 2004 / 아동의 모발 내 무기물 농동와 주의력 결핍 및 과잉행동장애와의 상호연관성에 관한연구 / 한국환경보건학회지 30 (1) : 41 ~ 49
4. [학술지(정기간행물)] - Cho CS. / 1997 / Attention deficit hyperactivity disorder / J Korean Med Assoc 40 : 1122 ~ 1134
5. [학술지(정기간행물)] - Rampello L / 2006 / Tic disorders: from pathophysiology to treatment / J Neurol 253 : 1 ~ 15
2. [학술지(정기간행물)] - Kessler RC / 2005 / Faraone SV, et al. Patterns and predictors of attention-deficit/hyperactivity disorder persistence into adulthood: results from the national comorbidity survey replication / Biol Psychiatry 57 : 1442 ~ 1451
3. [학술지(정기간행물)] - 유연아 / 2004 / 아동의 모발 내 무기물 농동와 주의력 결핍 및 과잉행동장애와의 상호연관성에 관한연구 / 한국환경보건학회지 30 (1) : 41 ~ 49
4. [학술지(정기간행물)] - Cho CS. / 1997 / Attention deficit hyperactivity disorder / J Korean Med Assoc 40 : 1122 ~ 1134
5. [학술지(정기간행물)] - Rampello L / 2006 / Tic disorders: from pathophysiology to treatment / J Neurol 253 : 1 ~ 15
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UCI(KEPA) : I410-ECN-0101-2014-516-000731437