바터팽대부암의 치료성적

김용배; 김상범; 조응호; 최동욱; 방호윤; 이종인; 문난모

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자료유형: 학술저널

저자정보: 김용배 (Korea Institute of Radiological and Medical Science) 김상범 (Korea Institute of Radiological and Medical Science) 조응호 (Korea Institute of Radiological and Medical Science) 최동욱 (SungKyunKwan University School of Medicine) 방호윤 (Korea Institute of Radiological and Medical Science) 이종인 (Korea Institute of Radiological and Medical Science) 문난모 (Korea Institute of Radiological and Medical Science)

저널정보: 한국간담췌외과학회 Annals of Hepato-Biliary-Pancreatic Surgery 한국간담췌외과학회지 제13권 제1호

발행연도: 2009.3

수록면: 49 - 53 (5page)

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Introduction: The prognosis of peri-ampullary cancer is poor because of its low respectability and high recurrence rate. Yet cancer of the Ampulla of Vater(AOV) has a relatively good prognosis. The aim of this study is to investigate the outcomes and to determine the factors that affect the survival rate of patients who underwent curative resection for AOV cancer.
Methods: From August 1988 to January 2008, 54 patients underwent curative resection for AOV cancer. We retrospectively reviewed the clinocopathologic data. The median follow up period was 45 months.
Results: Twenty-seven pancreaticoduodenectomies (PD) and 27 pyrolus-preserving pancreaticoduodenectomies (PPPD) were performed. There was no hospital mortality, but 25 out of 54 patients (47.3%) experienced postoperative complications. The 5-year overall survival (OS) rate was 53.97% and the 5-year disease free survival (DFS) rate was 51.75%. On multivariate analysis, the variables that affected the overall survival rate and the disease free survival rate was poor histologic differentiation (p<0.001).
Conclusions: Although the AOV cancer is one of the periampullary cancers that have a very poor outcome, long-term survival and favorable outcomes can be achieved after a curative resection. In this study, poor-histologic differentiation was the only independent factor for a poor prognosis.

#Ampulla of Vater #Carcinoma #Prognosis #바터팽대부 #상피암 #예후

참고문헌 (18)

참고문헌 신청

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2. [학술지(정기간행물)] - Yamaguchi K / 1987 / Carcinoma of the ampulla of Vater. A clinicopathologic study and pathologic staging of 109 cases of carcinoma and 5 cases of adenoma / Cancer 59 : 506 ~ 515

3. [학술지(정기간행물)] - Nakase A / 1977 / Surgical treatment of cancer of the pancreas and the periampullary region: Cumulative results in 57 institutions in japan / Ann Surg 185 : 52 ~ 57

4. [학술지(정기간행물)] - Howe JR / 1998 / Factors predictive of survival in ampullary carcinoma / Ann Surg 228 : 87 ~ 94

5. [학술지(정기간행물)] - Yeo CJ / 1998 / Periampullary adenocarcinoma: Analysis of 5-year survivors / Ann Surg 227 : 821 ~ 831

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