지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.3
- 수록면
- 37 - 41 (5page)
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Purpose: The aim of this study is to determine whether the serum apolipoprotein A1(apoA1) level, as measured at different time points after hepatectomy and liver transplantation, can predict the synthesis ability of the liver and the nutritional status. We also investigated the usefulness of regions of interest(ROIs) as an indicator of the recovery status of the liver after liver transplantation.
Methods: 93 patients (21: laparoscopic cholecystectomy, 53: partial hepatectomy, 19: liver transplantation) were operated on under general anesthesia. The serum levels of apoA1, prealbumin, albumin, aspartate aminotransferase and alanine aminotransferase and the prothrombin time were measured at pre- and post-operation. The liver conditions were a normal liver (50 cases), hepatitis (16 cases) and liver cirrhosis (28 cases). The mean hepatic attenuation was calculated by averaging the ROI values that were obtained at different hepatic segments.
Results: The serum apoA1 level was minimally changed during the perioperative period in the laparoscopic cholecystectomy group. Yet in most cases, the serum apoA1 level after partial hepatectomy and liver transplantation was decreased on postoperative days (PODs) 1 and 7, but it nearly recovered to the preoperative level on POD 30. There were significant differences I the values of apoA1 between the normal liver and co-existent liver disease at the various time points. The ROI value after transplantation gradually increased and it reached a normal level by POD 30.
Conclusion: The serum apoA1 level can be an indicator of liver’s ability to synthesize protein and the nutritional status after partial hepatectomy. In addition, ROIs of the unenhanced CT image can reflect the recovery status of the liver after transplantation.
Methods: 93 patients (21: laparoscopic cholecystectomy, 53: partial hepatectomy, 19: liver transplantation) were operated on under general anesthesia. The serum levels of apoA1, prealbumin, albumin, aspartate aminotransferase and alanine aminotransferase and the prothrombin time were measured at pre- and post-operation. The liver conditions were a normal liver (50 cases), hepatitis (16 cases) and liver cirrhosis (28 cases). The mean hepatic attenuation was calculated by averaging the ROI values that were obtained at different hepatic segments.
Results: The serum apoA1 level was minimally changed during the perioperative period in the laparoscopic cholecystectomy group. Yet in most cases, the serum apoA1 level after partial hepatectomy and liver transplantation was decreased on postoperative days (PODs) 1 and 7, but it nearly recovered to the preoperative level on POD 30. There were significant differences I the values of apoA1 between the normal liver and co-existent liver disease at the various time points. The ROI value after transplantation gradually increased and it reached a normal level by POD 30.
Conclusion: The serum apoA1 level can be an indicator of liver’s ability to synthesize protein and the nutritional status after partial hepatectomy. In addition, ROIs of the unenhanced CT image can reflect the recovery status of the liver after transplantation.
목차
서론
대상 및 방법
결과
고찰
참고문헌
참고문헌 (13)
참고문헌 신청
1. [학술지(정기간행물)] - Takahashi T / 2004 / Safe and permissible limits of hepatectomy in obstructive jaundice patients / World J Surg 28 : 475 ~ 81
2. [학술지(정기간행물)] - Kawamoto M / 2006 / Serum lipid and lipoprotein alterations represent recovery of liver function after hepatectomy / Liver Int 26 : 203 ~ 10
3. [학술지(정기간행물)] - Schneider P D / 2004 / Preoperative assessment of liver function / Surg Clin N Am 84 : 355 ~ 73
4. [학술지(정기간행물)] - Pelton J J / 1998 / Comparison of liver function tests after hepatic lobectomy and hepatic wedge resection / Am Surg 64 : 408 ~ 14
5. [학술지(정기간행물)] - Katsuramaki T / 2006 / Assessment of nutritional status and prediction of postoperative liver function from serum apolioprotein A-1 levels with hepatectomy / World J Surg 30 : 1886 ~ 91
2. [학술지(정기간행물)] - Kawamoto M / 2006 / Serum lipid and lipoprotein alterations represent recovery of liver function after hepatectomy / Liver Int 26 : 203 ~ 10
3. [학술지(정기간행물)] - Schneider P D / 2004 / Preoperative assessment of liver function / Surg Clin N Am 84 : 355 ~ 73
4. [학술지(정기간행물)] - Pelton J J / 1998 / Comparison of liver function tests after hepatic lobectomy and hepatic wedge resection / Am Surg 64 : 408 ~ 14
5. [학술지(정기간행물)] - Katsuramaki T / 2006 / Assessment of nutritional status and prediction of postoperative liver function from serum apolioprotein A-1 levels with hepatectomy / World J Surg 30 : 1886 ~ 91
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UCI(KEPA) : I410-ECN-0101-2014-514-001253849