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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.11
- 수록면
- 380 - 384 (5page)
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초록· 키워드
오류제보하기
Purpose: Tertiary hyperparathyroidism (THPT) occurs in less than 8% of the patients with secondary hyperparathyroidism after successful kidney transplantation. Tertiary hyperparathyroidism is commonly due to parathyroid hyperplasia, but about 2.6% of the THPT cases may be due to single or double adenomas. We investigate the usefulness of limited resection of single or two-gland parathyroid by comparing the blood calcium and PTH levels with respect to operative strategy.
Methods: We analyzed a total of 13 cases of tertiary hyperparathyroidism that were diagnosed and operated on at Asan Medical Center from May 1996 to April 2005. The patients were grouped according to the operative strategy: 3 and 1/2-parathyroidectomy (n=5), 3-parathyroidectomy (n=6), and 2-parathyroidectomy (n=2), and then we compared the mean blood PTH, calcium and creatinine levels. One patient in the 3-parathyroidectomy group underwent hemodialysis due to kidney transplant rejection, and this data was excluded from the analysis.
Results: The mean blood calcium and PTH levels of the 2-parathyroidectomy group were higher than that of the other two groups. There were no cases of transient hypocalcemia in the 3 groups (＜7.5 ㎎/㎗), and there were no cases of hypercalcemia at one year postoperative in the 3 &1/2-parathyroidectomy and 2-parathyroidectomy groups. The blood calcium and blood PTH levels were less than 9.1 ㎎/㎗ and more than 100 pg/㎖, respectively, in the one 3-parathyroidectomy patient who underwent hemodialysis due to kidney transplant rejection.
Conclusion: Our preliminary conclusions, based on our small groups and the short follow-up period, are that the blood calcium and PTH levels will be higher in the limited resection group if kidney transplant rejection occurs, and tumor recurrence will be also more often found in the limited resection group. Therefore, our recommendation is that 3 and 1/2-parathyroidectomy and 2-parathyroidectomy are preferable operative strategies for tertiary hyperparathyroidism.
Methods: We analyzed a total of 13 cases of tertiary hyperparathyroidism that were diagnosed and operated on at Asan Medical Center from May 1996 to April 2005. The patients were grouped according to the operative strategy: 3 and 1/2-parathyroidectomy (n=5), 3-parathyroidectomy (n=6), and 2-parathyroidectomy (n=2), and then we compared the mean blood PTH, calcium and creatinine levels. One patient in the 3-parathyroidectomy group underwent hemodialysis due to kidney transplant rejection, and this data was excluded from the analysis.
Results: The mean blood calcium and PTH levels of the 2-parathyroidectomy group were higher than that of the other two groups. There were no cases of transient hypocalcemia in the 3 groups (＜7.5 ㎎/㎗), and there were no cases of hypercalcemia at one year postoperative in the 3 &1/2-parathyroidectomy and 2-parathyroidectomy groups. The blood calcium and blood PTH levels were less than 9.1 ㎎/㎗ and more than 100 pg/㎖, respectively, in the one 3-parathyroidectomy patient who underwent hemodialysis due to kidney transplant rejection.
Conclusion: Our preliminary conclusions, based on our small groups and the short follow-up period, are that the blood calcium and PTH levels will be higher in the limited resection group if kidney transplant rejection occurs, and tumor recurrence will be also more often found in the limited resection group. Therefore, our recommendation is that 3 and 1/2-parathyroidectomy and 2-parathyroidectomy are preferable operative strategies for tertiary hyperparathyroidism.
목차
서론
방법
결과
고찰
결론
REFERENCES
참고문헌 (19)
참고문헌 신청
1. [학술지(정기간행물)] - D`Alessandro AM / 1989 / Tertiary hyperparathyroidism after renal transplantation: operative indication. / Surgery 106 : 1049 ~ 1055
2. [학술지(정기간행물)] - Kilgo MS / 1988 / Tertiary hyperparathyroidism after renal transplantation: surgical strategy / Surgery 124 : 677 ~ 683
3. [학술지(정기간행물)] - Nieto J / 1997 / Tertiary hyperparathyroidism after renal transplantation / Pediatr Nephrol 11 : 65 ~ 68
4. [학술지(정기간행물)] - Tominaga Y / 1996 / Clonal analysis of nodular parathyroid hyperplasia in renal hyperparathyroidism / Word J Surg 20 : 744 ~ 752
5. [학술지(정기간행물)] - Decker PA / 2001 / Subtotal parathyroidectomy in renal failure: still needed after all these years / World J Surg 25 : 708 ~ 712
2. [학술지(정기간행물)] - Kilgo MS / 1988 / Tertiary hyperparathyroidism after renal transplantation: surgical strategy / Surgery 124 : 677 ~ 683
3. [학술지(정기간행물)] - Nieto J / 1997 / Tertiary hyperparathyroidism after renal transplantation / Pediatr Nephrol 11 : 65 ~ 68
4. [학술지(정기간행물)] - Tominaga Y / 1996 / Clonal analysis of nodular parathyroid hyperplasia in renal hyperparathyroidism / Word J Surg 20 : 744 ~ 752
5. [학술지(정기간행물)] - Decker PA / 2001 / Subtotal parathyroidectomy in renal failure: still needed after all these years / World J Surg 25 : 708 ~ 712
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UCI(KEPA) : I410-ECN-0101-2013-514-002683007