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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.6
- 수록면
- 462 - 468 (7page)
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초록· 키워드
오류제보하기
Local invasion or distant metastasis is frequently seen in patients with anaplastic carcinoma at the time of presentation, and this is unlike the usual cases of pancreatic carcinoma. So most cases of anaplastic carcinoma are confirmed by autopsy. We report here on our experiences of two cases of the anaplastic pancreatic carcinoma that were confirmed by the postoperative pathology. From January 2006 to December 2006, two patients at Chung-Nam National University Hospital were postoperatively diagnosed as having anaplastic carcinoma of the pancreas. The clinicopathologic data of these patients was reviewed. Case 1) A seventy-years-old male was admitted to our hospital due to his left abdominal pain. On physical examination, there was ill-defined palpable mass on the left upper abdomen. The CA 19-9 level was 4.8 (U/㎖). On the abdominal CT scans, a 14.8 cm sized cystic mass with a mild enhancing internal solid portion was detected. He underwent distal pancreatectomy, total gastrectomy and segmental resection of the transverse colon due to direct invasion. The mass was pathologically confirmed as anaplastic pancreatic carcinoma. Postoperatively 3 months later, multiple liver and lymph node metastases were detected on the follow-up CT scan. Case 2) A sixty-five years-old female was referred to our department for a splenic hilar mass that involved the distal pancreas. The CA19-9 level was 3.18 (U/㎖). On the preoperative CT scan, an 8.0 cm sized irregular mass with heterogenous contrast enhancement was detected on the tail of the pancreas. She underwent distal pancreatectomy with splenectomy and segmental resection of the transverse colon due to direct invasion. On the pathology report, the pancreatic mass was revealed to be anaplastic carcinoma of the pancreas. One month later, a recurred pancreatic mass and multiple liver and peritoneal metastases were detected on the follow-up CT scan. Anaplastic pancreatic carcinomas show distinctive aggressive behavior and a dismal prognosis.
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증례
고찰
REFERENCES
참고문헌 (29)
참고문헌 신청
1. [학술지(정기간행물)] - Chen J / 1985 / Morphological study of 391 cases of exocrine pancreatic tumours with special reference to the classification of exocrine pancreatic carcinoma / J Pathol 146 : 17 ~ 29
2. [학술지(정기간행물)] - Tschang TP / 1977 / Pleomorphic carcinoma of pancreas: pleomorphic carcinoma of pancreas / An analysis of 15 cases. Cancer 39 : 2114 ~ 2126
3. [학술지(정기간행물)] - Paal E / 2001 / A clinicopathologic and immunohistochemical Study of 35 anaplastic carcinomas of the pancreas with a review of the literature / Ann Diagn Pathol 5 : 129 ~ 140
4. [학술지(정기간행물)] - Zamboni G / 2000 / Pancreatic head mass: what can be done? Classification: the pathological point of view / JOP 1 : 77 ~ 84
5. [학술지(정기간행물)] - Ichikawa T / 2000 / Atypical exocrine and exdocrine pancreatic tumors (anaplastic, small cell and giant cell types): CT and pathologic features in 14 patients / Abdom Imaging 25 : 409 ~ 419
2. [학술지(정기간행물)] - Tschang TP / 1977 / Pleomorphic carcinoma of pancreas: pleomorphic carcinoma of pancreas / An analysis of 15 cases. Cancer 39 : 2114 ~ 2126
3. [학술지(정기간행물)] - Paal E / 2001 / A clinicopathologic and immunohistochemical Study of 35 anaplastic carcinomas of the pancreas with a review of the literature / Ann Diagn Pathol 5 : 129 ~ 140
4. [학술지(정기간행물)] - Zamboni G / 2000 / Pancreatic head mass: what can be done? Classification: the pathological point of view / JOP 1 : 77 ~ 84
5. [학술지(정기간행물)] - Ichikawa T / 2000 / Atypical exocrine and exdocrine pancreatic tumors (anaplastic, small cell and giant cell types): CT and pathologic features in 14 patients / Abdom Imaging 25 : 409 ~ 419
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UCI(KEPA) : I410-ECN-0101-2013-514-002691314