지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.7
- 수록면
- 27 - 31 (5page)
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초록· 키워드
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Purpose: The presence or absence of lymph node metastasis is significantly associated with the survival of patients with gastric carcinoma. We compared node-positive and node-negative mucosal gastric carcinoma patients to identif y the clinicopathological characteristics of node-positive mucosal gastric carcinoma. We also evaluated the variables associated with lymph node metastasis and survival in this group of patients.
Methods: Of the 580 mucosal gastric carcinoma patients, 32 (5.5%) were node-positive. A statistical analysis using the Cox model was performed to determine the factors that can predict the patients’ outcomes.
Results: The mean tumor size was significantly larger in the patients with node-positive mucosal gastric carcinoma than that in the node-negative patients (3.3 vs. 1.8 cm; P＜0.001). The overall survival rate was lower for the patients who were node-positive than for the patients who were node-negative (83.3% vs. 91.4%, respectively), but the difference was not significant (P＞0.05). Using the Cox proportional hazard regression model, tumor size was an independent statistically significant parameter associated with lymph node metastasis (risk ratio: 4.70, 95% confidence interval: 1.20 to 18.35; P＜0.05).
Conclusion: Tumor size is the most reliable predictor of lymph node metastasis for patients with node-positive mucosal gastric carcinoma. Nevertheless, a large tumor size is not associated with a poor outcome for patients with node-positive mucosal gastric carcinoma. The patients with node-positive mucosal gastric carcinoma showed good survival rates after undergoing gastrectomy and extensive node dissection.
Methods: Of the 580 mucosal gastric carcinoma patients, 32 (5.5%) were node-positive. A statistical analysis using the Cox model was performed to determine the factors that can predict the patients’ outcomes.
Results: The mean tumor size was significantly larger in the patients with node-positive mucosal gastric carcinoma than that in the node-negative patients (3.3 vs. 1.8 cm; P＜0.001). The overall survival rate was lower for the patients who were node-positive than for the patients who were node-negative (83.3% vs. 91.4%, respectively), but the difference was not significant (P＞0.05). Using the Cox proportional hazard regression model, tumor size was an independent statistically significant parameter associated with lymph node metastasis (risk ratio: 4.70, 95% confidence interval: 1.20 to 18.35; P＜0.05).
Conclusion: Tumor size is the most reliable predictor of lymph node metastasis for patients with node-positive mucosal gastric carcinoma. Nevertheless, a large tumor size is not associated with a poor outcome for patients with node-positive mucosal gastric carcinoma. The patients with node-positive mucosal gastric carcinoma showed good survival rates after undergoing gastrectomy and extensive node dissection.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (23)
참고문헌 신청
1. [학술지(정기간행물)] - Bozzetti F / 1986 / A multifactorial approach for the prognosis of patients with carcinoma of the stomach after curative resection / Surg Gynecol Obstet 162 : 229 ~ 234
2. [학술지(정기간행물)] - Maruyama K / 1987 / The most important prognostic factors for gastric cancer patients / Scand J Gastroenterol 22 : 63 ~ 68
3. [학술지(정기간행물)] - Adachi Y / 1994 / A clinicopathologic study of gastric carcinoma with reference to age of patients / J Clin Gastroenterol 18 : 287 ~ 290
4. [학술지(정기간행물)] - Siewert Jr / 1998 / Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study / Ann Surg 228 : 449 ~ 461
5. [학술지(정기간행물)] - Yamaguchi T / 2001 / Node-positive mucosal gastric cancer: a follow-up study / Jpn J Clin Oncol 31 : 153 ~ 156
2. [학술지(정기간행물)] - Maruyama K / 1987 / The most important prognostic factors for gastric cancer patients / Scand J Gastroenterol 22 : 63 ~ 68
3. [학술지(정기간행물)] - Adachi Y / 1994 / A clinicopathologic study of gastric carcinoma with reference to age of patients / J Clin Gastroenterol 18 : 287 ~ 290
4. [학술지(정기간행물)] - Siewert Jr / 1998 / Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study / Ann Surg 228 : 449 ~ 461
5. [학술지(정기간행물)] - Yamaguchi T / 2001 / Node-positive mucosal gastric cancer: a follow-up study / Jpn J Clin Oncol 31 : 153 ~ 156
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UCI(KEPA) : I410-ECN-0101-2013-514-002691112