지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.9
- 수록면
- 195 - 202 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: Branch duct type intraductal papillary mucinous neoplasms (Br-IPMN) have better prognosis and lower malignancy rate than do main duct type IPMNs (M-IPMN). However, surgical resection is necessary when malignancy is suspected, and radical resection should be performed in cases of invasive IPMN. The objectives of this study were to investigate the characteristics of Br-IPMN and related predictive malignancy/invasiveness factors and to present a standardized scoring system for predicting pathologic results.
Methods: We conducted a retrospective review of 91 patients diagnosed with Br-IPMNs between 1998 and 2007. Mean patient age was 62.5±9.0 years. Eighty (87.9%) patients had benign IPMNs (17 adenoma, 63 borderline malignancy), and 11 (12.1%) patients had malignant IPMNs (4 carcinoma in situ, 7 invasive carcinoma). Eighty-four (92.3%) patients had noninvasive IPMN, and 7 (7.7%) patients had invasive IPMN.
Results: The size of the cystic mass and the presence and size of the mural nodule were found by univariate analysis to be significantly different between the benign and malignant groups. History of DM, size of the cystic mass, size of the mural nodule, and thickness of the cystic wall were significantly different between the noninvasive and invasive IPMN groups on univariate analysis. The regression coefficients for the size of the cystic mass and for the size and presence of the mural nodule were calculated using multivariate analysis, and the scores predicting malignant and invasive IPMN determined (P=0.001, P=0.000, respectively).
Conclusion: There are no universally held guidelines for surgical management of Br-IPMN patients. Hence, many clinicians have difficulty deciding the specific character of the resection they will pursue. By using malignancyand invasiveness-predicting scores, we expect that much of this difficulty can be avoided in the future.
Methods: We conducted a retrospective review of 91 patients diagnosed with Br-IPMNs between 1998 and 2007. Mean patient age was 62.5±9.0 years. Eighty (87.9%) patients had benign IPMNs (17 adenoma, 63 borderline malignancy), and 11 (12.1%) patients had malignant IPMNs (4 carcinoma in situ, 7 invasive carcinoma). Eighty-four (92.3%) patients had noninvasive IPMN, and 7 (7.7%) patients had invasive IPMN.
Results: The size of the cystic mass and the presence and size of the mural nodule were found by univariate analysis to be significantly different between the benign and malignant groups. History of DM, size of the cystic mass, size of the mural nodule, and thickness of the cystic wall were significantly different between the noninvasive and invasive IPMN groups on univariate analysis. The regression coefficients for the size of the cystic mass and for the size and presence of the mural nodule were calculated using multivariate analysis, and the scores predicting malignant and invasive IPMN determined (P=0.001, P=0.000, respectively).
Conclusion: There are no universally held guidelines for surgical management of Br-IPMN patients. Hence, many clinicians have difficulty deciding the specific character of the resection they will pursue. By using malignancyand invasiveness-predicting scores, we expect that much of this difficulty can be avoided in the future.
목차
서론
방법
결과
고찰
결론
REFERENCES
참고문헌 (23)
참고문헌 신청
1. [학술지(정기간행물)] - Sohn TA / 2004 / Intraductal papillary mucinous neoplasms of the pancreas: an updated experience / Ann Surg 239 : 788 ~ 797
2. [학술지(정기간행물)] - Ohashi K / 1982 / Four cases of mucous secreting pancreatic cancer / Prog Digest Endosc 20 : 348 ~ 351
3. [학술지(정기간행물)] - Longnecker DS / 2005 / Histopathological diagnosis of pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms: interobserver agreement / Pancreas 31 : 344 ~ 349
4. [학술지(정기간행물)] - Tanaka M / 2006 / International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas / Pancreatology 6 : 17 ~ 32
5. [학술지(정기간행물)] - Jang JY / 2008 / Treatment guidelines for branch duct type intraductal papillary mucinous neoplasms of the pancreas: when can we operate or observe / Ann Surg Oncol 15 : 199 ~ 205
2. [학술지(정기간행물)] - Ohashi K / 1982 / Four cases of mucous secreting pancreatic cancer / Prog Digest Endosc 20 : 348 ~ 351
3. [학술지(정기간행물)] - Longnecker DS / 2005 / Histopathological diagnosis of pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms: interobserver agreement / Pancreas 31 : 344 ~ 349
4. [학술지(정기간행물)] - Tanaka M / 2006 / International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas / Pancreatology 6 : 17 ~ 32
5. [학술지(정기간행물)] - Jang JY / 2008 / Treatment guidelines for branch duct type intraductal papillary mucinous neoplasms of the pancreas: when can we operate or observe / Ann Surg Oncol 15 : 199 ~ 205
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
췌관내 유두상 점액 종양의 임상상 및 병리학적 특징: 악성 종양 예측인자를 중심으로
대한내과학회지
2007 .01
-
침윤성 췌관내 유두상 점액종양의 임상적 특징과 치료 결과 : 췌관선암과의 비교
Annals of Surgical Treatment and Research
2007 .04
-
Predictors of Malignancy in “Pure” Branch-Duct Intraductal Papillary Mucinous Neoplasm of the Pancreas without Enhancing Mural Nodules on CT Imaging: A Nationwide Multicenter Study
Gut and Liver
2018 .01
-
Predictive factors for invasive intraductal papillary mucinous neoplasm of the pancreas
Annals of Hepato-Biliary-Pancreatic Surgery
2011 .12
-
Branch duct intraductal papillary mucinous neoplasm of the pancreas : single-center experience with 324 patients who underwent surgical resection
Annals of Hepato-Biliary-Pancreatic Surgery
2015 .08
-
십이지장 샘암종과 동반된 악성 췌관 내 유두상 점액 종양 1예
Clinical Endoscopy
2011 .01
-
Surgical outcomes of multifocal branch duct intraductal papillary mucinous neoplasms of pancreas
Annals of Hepato-Biliary-Pancreatic Surgery
2014 .11
-
췌장의 낭종성 질환-수술 혹은 경과관찰
대한내과학회지
2010 .01
-
분할 췌와 동반된 유두상 점액성 종양 (Intraductal Papillary Mucinous Neoplasm) 1예
Clinical Endoscopy
2006 .01
-
췌장 낭성종양과 췌관내 유두상 점액종양에 대한 임상적 고찰
Annals of Surgical Treatment and Research
2001 .11
-
간이식 환자에서의 췌관내유두상점액종양
Annals of Hepato-Biliary-Pancreatic Surgery
2008 .06
-
췌관 내 유두상 점액 종양을 동반한 동시성 원발성 삼중복암
Annals of Surgical Treatment and Research
2008 .07
-
Factors Predictive of Malignancy Potency in Pure Branch Duct Intraductal Papillary Mucinous Neoplasm of the Pancreas without Mural Nodules
Gut and Liver
2018 .01
-
담관내 유두상 점액 종양
Annals of Surgical Treatment and Research
2007 .09
-
분지 췌관형 췌관내 유두상 점액종양의 외과적 치료
Annals of Surgical Treatment and Research
2006 .04
-
췌관 내 점액성 유두 종양에 의해 형성된 췌위루 1예
Clinical Endoscopy
2006 .01
-
췌관내 유두상점액종양의 임상적 특징 및 예후
대한내과학회지
2014 .01
-
Types and recurrence of IPMN after resection
한국간담췌외과학회 학술대회지
2015 .09
-
분지 췌관형 췌관내 유두상 점액종양의 외과적 치료
대한외과학회 학술대회 초록집
2005 .10
-
Preoperative factors predicting malignancy and diagnostic scoring system in IPMN of the pancreas
대한외과학회 학술대회 초록집
2009 .11
이 논문의 저자 정보
이 논문과 함께 이용한 논문
Intrahepatic and extrahepatic intraductal papillary neoplasms of bile duct
Myunghee Yoon
Annals of Hepato-Biliary-Pancreatic Surgery
2013
.03
Clinical and Histologic Characteristics of Intraductal Papillary Neoplasms of the Bile Ducts : Comparison with Pancreatic Intraductal Papillary Mucinous Neoplasms
Mee Joo Kang
,
Kyoung Bun Lee
,
Jin-Young Jang
외 6명
한국간담췌외과학회 학술대회지
2012
.04
췌장의 점액성 낭포종양과 췌관내 유두상 점액성종양의 비교
배병진
,
김용훈
,
강구정
외 1명
Annals of Hepato-Biliary-Pancreatic Surgery
2002
.06
췌관내 유두상 점액성 종양(IPMT)의 외과적 치료
조재형
,
박선진
,
이상목
외 2명
Annals of Hepato-Biliary-Pancreatic Surgery
2007
.03
췌관내유두상점액종과 췌장 점액성낭종의 감별을 위한 분자생물학적 지표의 탐색
장진영
,
이승은
,
황대욱
외 5명
Annals of Hepato-Biliary-Pancreatic Surgery
2008
.06
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2013-514-002690004