지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.12
- 수록면
- 481 - 485 (5page)
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초록· 키워드
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Purpose: Muscular artery differs from elastic artery in physical properties and constituents of the arterial wall. To investigate the difference between muscular and elastic arteries, we measured the pulse wave velocities (PWVs) in lower extremity muscular arteries (femoral ankle PWV, faPWV) and abdominal elastic arteries (brachial femoral PWV, bfPWV), and searched for the relationships between the PWVs of muscular, elastic arteries and the risk factors of arteriosclerosis.
Methods: 184 normal volunteers were enrolled in the study. Among them, the ratios of male/female, smoker/non-smoker, and hypertension/normal were 81/103, 66/118, and 63/121, respectively. Using volume plethysmography, faPWV and bfPWV were measured. The risk factors of arteriosclerosis in this study were age, gender, smoking, hypertension, body mass index, low density lipoprotein, high density lipoprotein, triglyceride, hemoglobin A1C, and white blood cell.
Results: The PWVs of lower extremity muscular arteries (faPWVs) were significantly faster than those of abdominal elastic arteries (bfPWVs) (right, P＜0.001; left, P＜0.001) Multiple regression analysis revealed that the independent risk factors of the PWV were age (right, P＜0.001; left, P＜0.001) and gender (right, P=0.008; left, p=0.014) in abdominal elastic arteries. However, in lower extremity muscular arteries, hypertension (right, P＜0.001; left, P＜0.001) as well as age (right, P＜0.001; left, P＜0.001) and gender (right, P=0.009; left, P=0.001) were other significant independent risk factors.
Conclusion: The PWVs of lower extremity muscular arteries were significantly faster than those of abdominal elastic arteries. The significance of hypertension in faPWV suggests that hypertension is an important risk factor in inducing arterial stiffness, especially in lower extremity muscular arteries.
Methods: 184 normal volunteers were enrolled in the study. Among them, the ratios of male/female, smoker/non-smoker, and hypertension/normal were 81/103, 66/118, and 63/121, respectively. Using volume plethysmography, faPWV and bfPWV were measured. The risk factors of arteriosclerosis in this study were age, gender, smoking, hypertension, body mass index, low density lipoprotein, high density lipoprotein, triglyceride, hemoglobin A1C, and white blood cell.
Results: The PWVs of lower extremity muscular arteries (faPWVs) were significantly faster than those of abdominal elastic arteries (bfPWVs) (right, P＜0.001; left, P＜0.001) Multiple regression analysis revealed that the independent risk factors of the PWV were age (right, P＜0.001; left, P＜0.001) and gender (right, P=0.008; left, p=0.014) in abdominal elastic arteries. However, in lower extremity muscular arteries, hypertension (right, P＜0.001; left, P＜0.001) as well as age (right, P＜0.001; left, P＜0.001) and gender (right, P=0.009; left, P=0.001) were other significant independent risk factors.
Conclusion: The PWVs of lower extremity muscular arteries were significantly faster than those of abdominal elastic arteries. The significance of hypertension in faPWV suggests that hypertension is an important risk factor in inducing arterial stiffness, especially in lower extremity muscular arteries.
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서론
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결과
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REFERENCES
참고문헌 (19)
참고문헌 신청
1. [학술지(정기간행물)] - Mircoli L / 1999 / Heart rate-dependent stiffening of large arteries in intact and sympathectomized rats / Hypertension 34 : 598 ~ 602
2. [학술지(정기간행물)] - van der Loop FT / 1997 / Differentiation of smooth muscle cells in human blood vessels as defined by smoothelin, a novel marker for the contractile phenotype / Arterioscler Thromb Vasc Biol 17 : 665 ~ 671
3. [단행본] - Hallett JW / 2009 / Comprehensive Vascular and Endovascular Surgery. 2nd ed / Elsevier
4. [학술지(정기간행물)] - Carmo M / 2002 / Alteration of elastin, collagen and their cross-links in abdominal aortic aneurysms / Eur J Vasc Endovasc Surg 23 : 543 ~ 549
5. [학술지(정기간행물)] - Armour BS / 2007 / State-level prevalence of cigarette smoking and treatment advice, by disability status, United States, 2004 / Prev Chronic Dis 4 : A86 ~
2. [학술지(정기간행물)] - van der Loop FT / 1997 / Differentiation of smooth muscle cells in human blood vessels as defined by smoothelin, a novel marker for the contractile phenotype / Arterioscler Thromb Vasc Biol 17 : 665 ~ 671
3. [단행본] - Hallett JW / 2009 / Comprehensive Vascular and Endovascular Surgery. 2nd ed / Elsevier
4. [학술지(정기간행물)] - Carmo M / 2002 / Alteration of elastin, collagen and their cross-links in abdominal aortic aneurysms / Eur J Vasc Endovasc Surg 23 : 543 ~ 549
5. [학술지(정기간행물)] - Armour BS / 2007 / State-level prevalence of cigarette smoking and treatment advice, by disability status, United States, 2004 / Prev Chronic Dis 4 : A86 ~
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