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논문 기본 정보

자료유형
학술저널
저자정보
최은주 (건국대학교) 이창진 (건국대학교)
저널정보
한국체육과학회 한국체육과학회지 한국체육과학회지 제21권 제1호 (자연과학 편)
발행연도
2012.2
수록면
1,165 - 1,175 (11page)

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초록· 키워드

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The purpose of this study was to investigate how low-intensity exercise and silymarin administration effect into a gene on the MyoD, Myostatin and PEPCK in skeletal muscle. Subjects of investigation were classified into two groups in Sprage-Dawley rats. One group of subjects was performed with only exercise which was divided exercise group(EX), and the other group was performed with both silymarin administration and exercise(SIL+EX). Treadmill was used for training by rats which were given silymarin administration (50㎎/g/day) 30 minutes before exercising, and they were trained a low-intensity exercise (8m/min, 60min/day, 5 times a week). After analyzing with Real time-PCR, this experiment showed us that the revelation of mRNA of PEPCK at soleus muscle (SOL) was significantly increased more in SIL+EX than in EX. But, there was not significant difference between the two groups in Gastrocnemius muscle(GA). A mRNA revelation of Myostatin was not significant difference between EX and SIL+EX in SOL and GA. In MyoD, the revelation of mRNA at SOL was increased more in SIL+EX than in EX. But, there was not significant difference between the two groups in Gastrocnemius muscle(GA). As a result, SIL+EX in SOL are considered to be an improvement for exercising capabilities as they SIL+EX effect into a gene of MyoD, Myostatin and PEPCK which involves exercising capabilities.

목차

Abstract
Ⅰ. 서론
Ⅱ. 연구방법
Ⅲ. 결과
Ⅳ. 논의
Ⅴ. 결론
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UCI(KEPA) : I410-ECN-0101-2013-692-001764539