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논문 기본 정보

자료유형
학술저널
저자정보
Jae-Hyeok Heo (Seoul Medical Center) Soon-Tae Lee (Seoul National University Hospital) Min Jung Oh (Seoul National University Hospital) Hyun-Jung Park (Seoul National University Hospital) Ji-Young Shim (Seoul National University Hospital) Kon Chu (Seoul National University Hospital) Manho Kim (Seoul National University Hospital)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.35 No.4
발행연도
2011.12
수록면
457 - 461 (5page)

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초록· 키워드

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A 24-week randomized open-label study with Korean red ginseng (KRG) showed cognitive benefits in patients with Alzheimer"s disease. To further determine long-term effect of KRG, the subjects were recruited to be followed up to 2 yr. Cognitive function was evaluated every 12 wk using the Alzheimer"s Disease Assessment Scale (ADAS) and the Korean version of the Mini Mental Status Examination (K-MMSE) with the maintaining dose of 4.5 g or 9.0 g KRG per d. At 24 wk, there had been a significant improvement in KRG-treated groups. In the long-term evaluation of the efficacy of KRG after 24 wk, the improved MMSE score remained without significant decline at the 48th and 96th wk. ADAS-cog showed similar findings. Maximum improvement was found around week 24. ln conclusion, the effect of KRG on cognitive functions was sustained for 2 yr follow-up, indicating feasible efficacies of long-term follow-up for Alzheimer"s disease.

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INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES

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