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논문 기본 정보

자료유형
학술저널
저자정보
Kiyoshi Ohba (Hokkaido Tokachi Area Regional Food Processing Technology Center) Kyu-Ho Han (Obihiro University of Agriculture and Veterinary Medicine) Ruvini Liyanage (Obihiro University of Agriculture and Veterinary Medicine) Megumi Nirei (Obihiro University of Agriculture and Veterinary Medicine) Naoto Hashimoto (National Agricultural Research Center for Hokkaido Region) Ken-ichiro Shimada (Obihiro University of Agriculture and Veterinary Medicine) Mitsuo Sekikawa (Obihiro University of Agriculture and Veterinary Medicine) Keiko Sasaki (Hokkaido Tokachi Area Regional Food Processing Technology Center) Chi-Ho Lee (건국대학교) Michihiro Fukushima (Obihiro University of Agriculture and Veterinary Medicine)
저널정보
한국식품과학회 Food Science and Biotechnology Food Science and Biotechnology vol 17. no 6
발행연도
2008.12
수록면
1,178 - 1,184 (7page)

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The effect of some peptides on hepatoprotection and cecal fermentation against D-galactosamine (GalN)-treated rats was studied. In acute hepatic injury tests, serum alanine aminotransferase (ALT), aspartate aminotranferase (AST), and lactic dehydrogenase (LDH) activities were remarkably increased after injection of GalN. However, potato and soybean peptides significantly decreased GalN-induced alterations of serum ALT and AST activities. Hepatic thiobarbituric acidreactive substance (TBARS) concentration in GalN-treated groups fed potato and soybean peptides was significantly lower than that in GalN-treated control group. Hepatic glutathione level in the GalN-treated group fed potato peptide was significantly higher than that in GalN-treated control group. Furthermore, cecal Lactobacillus level in GalN-treated groups fed potato and soybean peptides was significantly higher than that in GalN-treated control group, and cecal short-chain fatty acid concentrations in GalN-treated group fed potato peptide were significantly higher than in GalN-treated control group. These results indicate that potato peptide may improve the cecal fermentation and prevent the GalN-induced liver damage in rats.

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Abstract
Introduction
Materials and Methods
Results and Discussion
Acknowledgments
References

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