지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.12
- 수록면
- 259 - 264 (6page)
이용수
초록· 키워드
오류제보하기
We examined the inhibitory effects of loquat methanol extract on the adhesion, migration, invasion and matrix metalloproteinase (MMP) activities of MDA-MB-231 human breast cancer cell line. Cells were cultured with DMSO or with 10, 25, or 50 ㎍/㎖ of loquat methanol extract. Both leaf and seed extracts significantly inhibited growth of MDA-MB-231 cells in a dose-dependent manner, although leaf extract was more effective. Adhesion and migration were significantly inhibited by loquat extracts in a dose-dependent manner. Loquat extract also inhibited the invasion of breast cancer cells in a dose-dependent manner and leaf extract was more effective than seed extract. MMP-2 and MMP-9 activities were also inhibited by loquat extract. Our results indicate that methanol extracts of loquat inhibit the adhesion, migration and invasion of human breast cancer cells partially through the inhibition of MMP activity and leaf extract has more anti-metastatic effects in cell based assay than seed extract. Clinical application of loquat extract as a potent chemopreventive agent may be helpful in limiting breast cancer invasion and metastasis.
목차
Abstract
Introduction
Materials and Methods
Results
Discussion
References
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Loquat (Eriobotrya japonica) extracts suppress the adhesion, migration and invasion of human breast cancer cell line
Nutrition Research and Practice
2009 .12
-
Loquat (Eriobotrya japonica) leaf extract inhibits the growth of MDA-MB-231 tumors in nude mouse xenografts and invasion of MDA-MB-231 cells
Nutrition Research and Practice
2016 .04
-
Loquat (Eriobotrya japonica) leaf extract inhibits the growth of MDA-MB-231 tumors in nude mouse xenografts and invasion of MDA-MB-231 cells
Nutrition Research and Practice
2016 .04
-
비파 부위별 에탄올 추출물의 항산화 활성 및 암세포 증식 억제효과
한국지역사회생활과학회지
2016 .05
-
Inhibitory effect of Erythronium japonicum on the human breast cancer cell metastasis
Nutrition Research and Practice
2015 .02
-
Inhibitory effect of Erythronium japonicum on the human breast cancer cell metastasis
Nutrition Research and Practice
2015 .02
-
Antioxidative and Antimicrobial Activity of Epicatechin Isolated from Leaves of Loquat( Eriobotrya japonica)
한국생명과학회 심포지움
2005 .04
-
비파가루를 첨가한 설기떡의 품질 특성
동아시아식생활학회지
2014 .12
-
Inhibitory activities of Perilla frutescens britton leaf extract against the growth, migration, and adhesion of human cancer cells
Nutrition Research and Practice
2015 .02
-
Inhibitory activities of Perilla frutescens britton leaf extract against the growth, migration, and adhesion of human cancer cells
Nutrition Research and Practice
2015 .02
-
Inorganic sulfur reduces the motility and invasion of MDA-MB-231 human breast cancer cells
Nutrition Research and Practice
2011 .10
-
Inorganic sulfur reduces the motility and invasion of MDA-MB-231 human breast cancer cells
Nutrition Research and Practice
2011 .10
-
Suppression of Metastasis of Human Breast Cancer Cells by Chitosan Oligosaccharides
Journal of Microbiology and Biotechnology
2009 .01
-
익모초 추출물의 항산화 효과 및 MCF-7 유방암 세포주의 성장억제 유도에 관한 연구
한국지역사회생활과학회지
2018 .11
-
오디 추출물의 혈관신생 억제 효과
생명과학회지
2008 .05
-
Anthocyanin계 성분인 Cyanidin이 인체 유방암세포 MDA-MB-231의 이동성과 침윤성에 미치는 영향
한국영양학회지
2008 .12
-
Triptolide inhibits ovarian cancer cell invasion by repression of matrix metalloproteinase 7 and 19 and upregulation of E-cadherin
Experimental and Molecular Medicine
2012 .01
-
Migration and invasion of drug-resistant lung adenocarcinoma cells are dependent on mitochondrial activity
Experimental and Molecular Medicine
2016 .01
-
Curcumin이 인체 유방암세포 MDA-MB-231 Cell의 전이 과정과 Matrix Metalloproteinase-9 활성에 미치는 영향
한국영양학회지
2006 .12
이 논문의 저자 정보
이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2012-594-004461070