지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.11
- 수록면
- 259 - 266 (8page)
이용수
초록· 키워드
오류제보하기
??The current study examined the effect of quercetin supplements on the lipid-lowering and antioxidant metabolism in ethanol-fed rats, The control group(E<sub>8</sub>) received ethanol only diet for 8 wks, whereas the other group(E<sub>8</sub>Q<sub>4</sub>) received a diet including quercetin supplementation(0.05%, wt/wt) for 4 wks while on the ethanol diet for 8wks. The hepatic alcohol dehydrogenase activity was significantly higher in the E<sub>8</sub>Q<sub>4</sub> group than in the E<sub>8</sub> group. Supplementation with quercetin significantly elevated the HDL- cholesterol concentration, the HDL-C/total-C ratio, and lowered the atherogenic index(AI) compared to the E<sub>8</sub> group. The hepatic triglyceride and cholesterol contents were significantly lowered by the quercetin supplement compared to those of the control group. The hepatic HMG-CoA reductase and ACAT activities of the E<sub>8</sub>Q<sub>4</sub>group were significantly lower than those of the E<sub>8</sub> group. The overall potential for antioxidant defense was significantly enhanced by the quercetin supplement, as indicated by a decrease in plasma and hepatic TBARS levels. The hepatic GSH-Px and G6PD activities were significantly higher in theE<sub>8</sub>Q<sub>4</sub> group compared to the E<sub>8</sub> group. The current results suggest that dietary quercetin leads to the inhibition of HMG-CoA reductase and ACAT, which in turn lowers cholesterol levels and normalizes antioxidant enzyme activities.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
Literature Cited
참고문헌 (44)
참고문헌 신청
[학술지(정기간행물)] - / 1999 / Nutritional and metabolic effects of alcoholism 15 : 583 ~ 589
[학술지(정기간행물)] - / 1993 / Biochemical factors in alcoholic liver disease 13 : 136 ~ 153
[학술지(정기간행물)] - / 2001 / Association between polymorphisms of ethanol metabolizing enzymes and susceptibility to alcoholic cirrhosis in a Korean male population 16 : 745 ~ 750
[학술지(정기간행물)] - / 1996 / Examination of coumarins flavonoids and polysaccharopeptide for antibacterial activity 27 : 1237 ~ 1240
[학술지(정기간행물)] - / 1995 / Chemoprevention of colon carcinogenesis by dietary curcumin a naturally occurring plant phenolic compound 55 : 259 ~ 266
[학술지(정기간행물)] - / 1993 / Biochemical factors in alcoholic liver disease 13 : 136 ~ 153
[학술지(정기간행물)] - / 2001 / Association between polymorphisms of ethanol metabolizing enzymes and susceptibility to alcoholic cirrhosis in a Korean male population 16 : 745 ~ 750
[학술지(정기간행물)] - / 1996 / Examination of coumarins flavonoids and polysaccharopeptide for antibacterial activity 27 : 1237 ~ 1240
[학술지(정기간행물)] - / 1995 / Chemoprevention of colon carcinogenesis by dietary curcumin a naturally occurring plant phenolic compound 55 : 259 ~ 266
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Effects of Normal Diet with or without Naringin Supplement Following Ethanol Diet on Changes in Lipid Profiles and Antioxidant Enzyme Activities in Rats
Nutritional Sciences
2006 .05
-
플라보노이드 화합물로부터 HMG-CoA reductase 저해 활성 물질 탐색
생명과학회지
2018 .02
-
고지방 식이를 섭취한 흰쥐에 있어서 Xylooligo당이 간의 HMG-CoA Reductase 활성 및 간조직의 형태학적 변화에 미치는 영향
한국영양학회지
2002 .12
-
Lovastatin을 생산하는 식용버섯 선발과 HMG-CoA reductase 저해 효과
미생물학회지
2006 .06
-
Polymorphisms of 3-hydroxy-3-methylglutaryl Coenzyme A Reductase Gene Are Not Associated with the Osteonecrosis of Femoral Head in Korean
생명과학회지
2008 .04
-
Bacillus cereus D-3로부터 항고지혈증 HMG-Coa Reductase 저해제의 생산
한국미생물·생명공학회지
2006 .01
-
비늘버섯으로부터 생리기능성 물질의 탐색
한국균학회지
2006 .01
-
Corn silk extract improves cholesterol metabolism in C57BL/6J mouse fed high-fat diets
Nutrition Research and Practice
2016 .10
-
Corn silk extract improves cholesterol metabolism in C57BL/6J mouse fed high-fat diets
Nutrition Research and Practice
2016 .10
-
Quercetin이 보리 자엽초에서 옥신에 의해 유도되는 에틸렌 생성에 미치는 영향
식물학회지
1992 .01
-
Effect of Structured Lipids Containing CLA on Hepatic Antioxidant Enzyme Activity in Rats Fed a Normal Diet
Nutritional Sciences
2004 .08
-
Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice
Nutrition Research and Practice
2012 .06
-
Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice
Nutrition Research and Practice
2012 .06
-
에탄올을 투여한 흰쥐 뇌조직의 항산화효소계 활성에 미치는 단백질과 섬유소의 영향
한국영양학회지
2000 .09
-
홍국과 보리를 이용하여 제조한 고추장의 특성과HMG-Co A Reductase 저해활성
한국미생물·생명공학회지
2007 .01
-
Effects of daily quercetin-rich supplementation on cardiometabolic risks in male smokers
Nutrition Research and Practice
2011 .02
-
Effects of daily quercetin-rich supplementation on cardiometabolic risks in male smokers
Nutrition Research and Practice
2011 .02
-
Different Inhibition of HMG CoA Reductase Inhibitors against HCV RNA Replication betweenHCV Genotypes 1b and 2a
한국미생물학회 학술대회논문집
2009 .05
-
인삼 추출물이 난소를 절제한 백서의 항산화효소 활성에 미치는 영향
생명과학회지
2002 .06
-
A Review on Structure, Modifications and Structure-Activity Relation of Quercetin and Its Derivatives
Journal of Microbiology and Biotechnology
2020 .01
이 논문의 저자 정보
이 논문과 함께 이용한 논문
Quercetin Reduces Obesity-induced Hepatosteatosis by Enhancing Mitochondrial Oxidative Metabolism via Home Oxygenase-1
Chu-Sook Kim
,
Yoonhee Kwon
,
Hoon Yoo
외 4명
한국식품영양과학회 학술대회발표집
2015
.08
Effect of Quercetin and Deferoxamine on Hepatic Gluconeogenesis and Steatosis and Adipose Tissue Inflammation in High Fat Fed ob/ob Mice
Jung-Eun Yim
,
Kyung-Ah Kim
,
Joo Sun Choi
한국식품영양과학회 학술대회발표집
2015
.08
양파 품종 및 색상에 따른 쿼세틴 함량과 항산화 효과
정효진
,
서종분
,
이야성
외 6명
한국원예학회 학술발표요지
2011
.10
Enhancement of Flavonol, Quercetin and Kaempferol, in Mulberry Leaf Fermented by Lactobacillus spp.
Jong Hoon JEONG
,
Nam Keun LEE
,
Elijah NYAKUDYA
외 5명
한국생물공학회 학술대회
2014
.04
Quercetin Glucoside Profiling of Fresh Onion ( Allium cepa) and Aged Black Onion Using HPLC-ESI/MS/MS
Dong-Min Chung
,
Sun Hwa Kwon
,
Young Chul Chung
외 1명
생명과학회지
2011
.03
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2012-594-004194285