지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.15 No.1
- 발행연도
- 2010.3
- 수록면
- 30 - 35 (6page)
이용수
초록· 키워드
오류제보하기
The potential biological activities of methanol extract and 5 fractions (hexane, CH₂Cl₂, EtOAc, BuOH and water) from roots of Astragalus membranaceus were examined by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, hydroxyl radical (·OH) scavenging activity, reducing power assays, lipid peroxidation inhibitory activity, α-amylase and α-glucosidase inhibition assays. The EtOAc fraction showed high DPPH free radical scavenging activity (EC??=170.34 ㎍/㎖), hydroxyl radical scavenging activity (EC??=32.14 ㎍/㎖), lipid peroxidation inhibitory activity (EC??=52.46 ㎍/㎖) and a concentration dependence, with OD value ranging from 0.234 to 0.345 0.1 to 0.5 ㎎/㎖), for reducing power. The EtOAc fraction has the highest total phenolic content (142.13 Gal μg/mg) and the CH2Cl2 fraction has the highest flavonoid content (71.63 Que ㎍/㎎). Meanwhile, hexane and EtOAc showed certain α-amylase and α-glucosidase inhibition activities. These results suggest that the methanol extract and fractions from Astragalus membranaceus root have significant antioxidant and anti-diabetes activities, which could be used as a potential source of pharmaceutical materials.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
CONCLUSION
ACKNOWLEDGEMENT
REFERENCES
참고문헌 (22)
참고문헌 신청
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2. [학술지(정기간행물)] - Parvaiz Ahmad / 2008 / Reactive Oxygen Species, Antioxidants and Signaling in Plants / Journal of Plant Biology(한국식물학회지) 51 (3) : 167 ~ 173
3. [학술지(정기간행물)] - Wood K.C. / 2008 / Sickle cell disease vasculopathy: a state of nitric oxide resistance / Free Radic. Biol. Med. 44 : 1506 ~ 1528
4. [학술지(정기간행물)] - Holman R.R. / 1999 / A randomized double-blind trial of acarbose in type 2 diabetes shows improved glycemic control over 3 years (U.K. Prospective Diabetes Study 44) / Diabetes Care 22 : 960 ~ 964
5. [학술지(정기간행물)] - Ells L.J. / 2005 / Postprandial glycaemic, lipaemic and haemostatic responses to ingestion of rapidly and slowly digested starches in healthy young women / Br. J. Nutr. 94 : 948 ~ 955
2. [학술지(정기간행물)] - Parvaiz Ahmad / 2008 / Reactive Oxygen Species, Antioxidants and Signaling in Plants / Journal of Plant Biology(한국식물학회지) 51 (3) : 167 ~ 173
3. [학술지(정기간행물)] - Wood K.C. / 2008 / Sickle cell disease vasculopathy: a state of nitric oxide resistance / Free Radic. Biol. Med. 44 : 1506 ~ 1528
4. [학술지(정기간행물)] - Holman R.R. / 1999 / A randomized double-blind trial of acarbose in type 2 diabetes shows improved glycemic control over 3 years (U.K. Prospective Diabetes Study 44) / Diabetes Care 22 : 960 ~ 964
5. [학술지(정기간행물)] - Ells L.J. / 2005 / Postprandial glycaemic, lipaemic and haemostatic responses to ingestion of rapidly and slowly digested starches in healthy young women / Br. J. Nutr. 94 : 948 ~ 955
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UCI(KEPA) : I410-ECN-0101-2010-511-002141883