지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.12
- 수록면
- 363 - 369 (7page)
이용수
초록· 키워드
오류제보하기
Musk, a dried preputial gland of musk animals, is one of the most famous and expensive chinese medicines. The present study investigated neuroprotective effect of the musk of the Ondatra zibethicus (MOZ) against ischemic insult in the gerbil hippocampal CA1 region after 5 min of transient cerebral ischemia. To elucidate the neuroprotective effect of MOZ on ischemic damage, 50 ㎎/㎏ MOZ was administered orally to gerbils for 7 days before the ischemic surgery, and we used cresyl violet, neuronal nuclei protein (NeuN) and Fluoro-Jade C (F-J C) staining. In the MOZ-treated group, many pyramidal neurons in the CA1 region were stained with cresyl violet and NeuN, and a few degenerative pyramidal neurons were stained with F-J C. The survival rate of the CA1 pyramidal neurons was about 60% compared to that in the vehicle-treated group. In the MOZ-treated group, ionized calcium binding adaptor molecule-1 (Iba-1, a marker for microgila) and isolectin B4 (IB4, a marker for activated microglia) immunoreactivity were significantly lower than that in the vehicle-treated group. These results suggest that repeated supplement of MOZ can protect neurons from ischemic damage.
목차
재료 및 방법
결과
고찰
감사의 글
참고문헌
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Extract of Diospyros kaki Stem Reduces Neuronal Damage in the Gerbil Hippocampus Induced by Transient Cerebral Ischemia
Laboratory Animal Research
2009 .06
-
Transient ischemia-induced change of CCR7 immunoreactivity in neurons and its new expression in astrocytes in the gerbil hippocampus
한국실험동물학회 학술발표대회 논문집
2013 .08
-
Pre-treated chrysanthemum indicum linne extract protects pyramidal neurons from transient cerebral ischemia via increasing antioxidants in the gerbil hippocampal CA1 region
한국실험동물학회 학술발표대회 논문집
2018 .01
-
Neuroprotection of Alpinia katsumadai Seed Extract against Neuronal Damage in the Ischemic Gerbil Hippocampus is Linked to Altered Brain-Derived Neurotrophic Factor
Laboratory Animal Research
2011 .03
-
Time interval after ischemic preconditioning affects neuroprotection and gliosis in the gerbil hippocampal CA1 region induced by transient cerebral ischemia
한국실험동물학회 학술발표대회 논문집
2015 .02
-
Cyclin D1 Immunoreactivity Changes in CA1 Pyramidal Neurons and Dentate Granule Cells in the Gerbil Hippocampus after Transient Forebrain Ischemia
한국실험동물학회 학술발표대회 논문집
2009 .08
-
Neuroprotective effects of risperidone against experimentally ischemic damage in the gerbil hippocampal CA1 region induced by transient global cerebral ischemia
한국실험동물학회 학술발표대회 논문집
2012 .08
-
Relationship between ischemic preconditioninginduced neuroprotection and antioxidants enzymes expressions in the gerbil hippocampal CA1 region following a subsequent lethal transient cerebral ischemia
한국실험동물학회 학술발표대회 논문집
2016 .02
-
Intermittent (alternate-day) fasting for three months increases calbindin D28k immunoreactivity in gerbil hippocampus but does not protect neurons against ischemia-reperfusion injury
한국실험동물학회 학술발표대회 논문집
2020 .07
-
Ischemic preconditioning-induced neuroprotection against transient cerebral ischemic damage via attenuating ubiquitin aggregation
한국실험동물학회 학술발표대회 논문집
2014 .08
-
Pre-treatment with laminarin protects hippocampal CA1 pyramidal neurons and attenuates reactive gliosis following transient forebrain ischemia in gerbils
한국실험동물학회 학술발표대회 논문집
2020 .02
-
Difference of fibroblast growth factor receptor 1 expression among CA1-3 regions of the gerbil hippocampus after transient cerebral ischemia
한국실험동물학회 학술발표대회 논문집
2010 .08
-
Protective effect of Chrysanthemum indicum Linne against ischemia-reperfusion injury by anti-inflammatory effect in gerbils
한국실험동물학회 학술발표대회 논문집
2015 .08
-
Neuronal expression of IL-6 in the CA1 region of gerbil hippocampus after global ischemia
대한체질인류학회 학술대회 연제 초록
2017 .06
-
Roles of HIF-1α, VEGF and NF-κB in ischemic preconditioning-mediated neuroprotection of hippocampal CA1 pyramidal neurons against a subsequent transient cerebral ischemia
한국실험동물학회 학술발표대회 논문집
2016 .08
-
Comparison of the immunoreactivities of NMDA receptors and calcium binding proteins between the young and adult hippocampal CA1 region induced by experimentally transient cerebral ischemia
한국실험동물학회 학술발표대회 논문집
2012 .08
-
Clinical and Electrophysiologic Responses to Acetylcholinesterase Inhibitors in MuSK-Antibody-Positive Myasthenia Gravis: Evidence for Cholinergic Neuromuscular Hyperactivity
Journal of Clinical Neurology
2014 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2010-510-001694215