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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.6
- 수록면
- 145 - 150 (6page)
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이 논문의 연구 히스토리 (3)
2009
Damage-Specific DNA Binding Protein 2 (DDB2) Splicing Variants in C57BL/6J Mouse
YoonYi Nam
,
Jun-Hong Pa
,
k
외 4명
한국실험동물학회 학술발표대회 논문집
2009.08
학술대회자료
Production and Characterization of Polyclonal Antibody to Transmembrane Inner Ear Protein
YoonYi Nam
,
Sanka
,
apandian Ka
외 5명
Laboratory Animal Research
2009.06
학술저널
Expression and Localization of Transmembrane Inner Ear Protein in C57BL/6J Mouse
YoonYi Nam
,
Ka
,
uppasamy Sanka
외 4명
한국실험동물학회 학술발표대회 논문집
2009.04
학술대회자료
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Deafness is one of the most common sensory deficits in human. Since the inner ears of mice and humans are anatomically and physiologically similar, mouse mutants allow us to reveal detailed analysis of defects in the cochlea and vestibular apparatus. Loss of function mutations in transmembrane inner ear (Tmie) protein has been shown to cause deafness in mice (circling, spinner) and humans (DFNB6). However, the detailed mechanism of Tmie protein in the cochlea still remains unclear. First step to achieve that purpose, we produced polyclonal antibody that recognize Tmie protein. The specifically selected amino acid sequence localized at the positions 118-133 (IPGEDKKKKKKDSVD) of Tmie protein has been used as immunogen to produce rabbit polyclonal antibody. Two rabbits were immunized with polypeptide and the serum was harvested from the rabbits served as the source of the polyclonal antibody specific to Tmie. Specificity of the antibody was determined by Western blot analysis. After transfection of tmiePC/pcDNA vector in HEK cells, we identified a specific band of tmie protein. Taken together, our anti-Tmie antibody can be useful for studying localization and characterization of Tmie protein.
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Subcellular localization of the transmembrane inner ear (Tmie) protein in a stable Tmie-expressing cell line
Laboratory Animal Research
2011 .12
-
Expression of deafness protein Tmie in postnatal developmental stages of C57BL/6J mice
Laboratory Animal Research
2012 .06
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Subcellular localization of transmembrane inner ear (Tmie) protein in a stable Tmie-expressing cell line
한국실험동물학회 학술발표대회 논문집
2012 .02
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Construction of Deafness Protein (TMIE) Expressing Stable Cell Line
한국실험동물학회 학술발표대회 논문집
2010 .08
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Tmie rescued lesion of circling mouse
한국실험동물학회 학술발표대회 논문집
2011 .02
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Tmie is Necessary Protein for Mechanotransduction of Hair Cells
한국실험동물학회 학술발표대회 논문집
2014 .02
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The Recovery Levels in the Circling Mouse with Transmembrane Inner Ear (tmie) Gene Are Dependent on the amount of Expression in the Cochlea
한국실험동물학회 학술발표대회 논문집
2010 .02
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The Different Recovery Levels in the Circling Mouse with Transmembrane Inner Ear (tmie) Gene are Dependent on the Pattern of Expression in the Cochlea
한국실험동물학회 학술발표대회 논문집
2010 .08
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Interaction of transmembrane inner ear (TMIE) protein with myosin7a and protocadherin15 proteins in the cochlea of circling mice
한국실험동물학회 학술발표대회 논문집
2016 .02
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Ectopic Expression of tmie Transgene Induces Various Recovery Levels of Behavior and Hearing Ability in the Circling Mouse
한국실험동물학회 학술발표대회 논문집
2008 .11
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Circling mouse has a 40Kb genomic deletion which includes transmembrane inner ear protein (tmie) gene
한국실험동물학회 학술발표대회 논문집
2008 .05
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The Different Rescue Levels in the Circling Mouse with Transmembrane Inner Ear (Tmie) Gene are Dependent on the Expression Patterns of Transgene in the Cochlea
한국실험동물학회 학술발표대회 논문집
2009 .08
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The different rescue levels in the circling mouse with Transmembrane inner ear (tmie) gene are dependent on the expression patterns of transgene in the cochlea
한국실험동물학회 학술발표대회 논문집
2008 .05
-
The different rescue levels in the circling mouse with Transmembrane inner ear (tmie) gene are dependent on the expression patterns of transgene in the cochlea
한국실험동물학회 학술발표대회 논문집
2008 .11
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Introduction of transmembrane inner ear (tmie) gene can recover the hearing impairment and abnormal behavior in the circling mouse
한국실험동물학회 학술발표대회 논문집
2008 .11
-
Introduction of transmembrane inner ear (tmie) gene can recover the hearing impairment and abnormal behavior in the circling mouse
한국실험동물학회 학술발표대회 논문집
2008 .05
-
Production and characterization of polyclonal antibody to transmembrane inner ear protein
한국실험동물학회 학술발표대회 논문집
2008 .11
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The entire structures of tmie and RN49018 are deleted in the circling mice
한국실험동물학회 학술발표대회 논문집
2010 .08
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The entire structures of tmie and RN49018 are deleted in the circling mice
한국실험동물학회 학술발표대회 논문집
2010 .02
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The Introduction of Tmie can Recover the Hearing and Balance Inability of the Circling Mice
한국실험동물학회 학술발표대회 논문집
2009 .08
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UCI(KEPA) : I410-ECN-0101-2009-510-018537606