지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.6
- 수록면
- 147 - 152 (6page)
이용수
초록· 키워드
오류제보하기
Lycopus lucidus Turcz is well known as traditional Chinese medicine, and it has been shown to exhibit antiinflammatory, -allergic and -oxidative effect. However, its anti-cancer properties have not been examined yet. In this study, we investigated the effect of the methanol extract of Lycopus lucidus Turcz on anti-cancer effect in MCF-7 human breast cancer cells. Treatment of Lycopus lucidus Turcz extract induced apoptosis and inhibition of cell proliferation in dose- and time-dependent manner. Apoptosis in the MCF-7 cells was characterized with the changes in nuclear morphology; decrease of Bcl-2 and caspase-7 expression; and increase of cleaved poly ADP-ribose polymerase (PARP). Furthermore, treatment of Lycopus lucidus Turcz extract caused the down-regulation of cell cycle-related protein including, cdk4, cyclin D1 and E2F-1. These results suggest that Lycopus lucidus Turcz might have the therapeutic value against human breast cancer cells.
목차
서론
재료 및 방법
결과
고찰
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
쉽싸리 부위별 물추출물의 항산화 활성
대한본초학회지(본초분과학회지)
2016 .01
-
Antioxidative Constituents from Lycopus lucidus
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
Immunodulatory activity of betulinic acid from Lycopus lucidus in murine macrophage RAW 264.7 cells
대한약학회 학술대회
2003 .01
-
Apoptotic Effects of 6-Gingerol in Human Breast Cancer Cells
International Journal of Oral Biology
2015 .01
-
참옻 추출물의 MCF-7 인체 유방암 세포에서 증식 억제효과
대한한의학방제학회지
2016 .01
-
Glehnia littoralis Root Extract Induces G0/G1 Phase Cell Cycle Arrest in the MCF-7 Human Breast Cancer Cell Line
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Panduratin A Inhibits Cell Proliferation by Inducing G0/G1 Phase Cell Cycle Arrest and Induces Apoptosis in Breast Cancer Cells
Biomolecules & Therapeutics(구 응용약물학회지)
2018 .01
-
Effects of Rapamycin on Cell Apoptosis in MCF-7 Human Breast Cancer Cells
Asian Pacific journal of cancer prevention : APJCP
2014 .01
-
택란의 비만세포 매개 즉시형 알레르기 반응의 억제 효과
약학회지
2002 .01
-
Momordica cochinchinensis Aril Extract Induced Apoptosis in Human MCF-7 Breast Cancer Cells
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Cadmium Induces Cell Cycle Arrest and Change in Expression of Cell Cycle Related Proteins in Breast Cancer Cell Lines
Toxicological Research
2005 .03
-
Roles of p53 and Caspases in Induction of Apoptosis in MCF-7 Breast Cancer Cells Treated with a Methanolic Extract of Nigella Sativa Seeds
Asian Pacific journal of cancer prevention : APJCP
2014 .01
-
知母 추출물이 MCF-7 세포의 생존율에 미치는 영향
대한한방내과학회지
2007 .01
-
인체 유방암 세포에서 retinoids의 영향에 대한 연구
한국환경성돌연변이·발암원학회지
2004 .06
-
20(S)-Protopanaxadiol Induces Human Breast Cancer MCF-7 Apoptosis through a Caspase-Mediated Pathway
Asian Pacific journal of cancer prevention : APJCP
2014 .01
-
Enhanced Anti-cancer Efficacy in MCF-7 Breast Cancer Cells by Combined Drugs of Metformin and Sodium Salicylate
대한의생명과학회지
2017 .09
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-510-018456080