메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색
질문

논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국생활환경학회 한국생활환경학회지 한국생활환경학회지 제16권 제2호
발행연도
2009.4
수록면
101 - 109 (9page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색
질문

초록· 키워드

오류제보하기
Currently, physical exercise is recommended as a therapeutic intervention to functional recovery in incomplete spinal cord injury patients. In the present study, we examined the effects of treadmill exercise on regeneration of corticospinal tracts and neurohysiological functional recovery after contusive spinal cord injury in rats. Adult rats were randomly assigned to one of three groups; (1) normal group; (2) SCI(contusion spinal cord injury) + sedentary group; (3) SCI(contusion spinal cord injury) + TMT(treadmill training exercise) group. One week after surgery, the treadmill exercise rats were exposed to treadmill low intensity exercise for 8 weeks. Using immunofluorescenestaining and anterograde tracing techniques, we identified enhanced axonal sprouting and regrowth in the corticospinal tracts after contusive spinal cord injury in rats with treadmill exercise. We also carried out western blot analysis to investigate axonal growth-associated protein (GAP-43) and Cdc2 expression in spinal cord. The neural functional assessment was determined by the BBB test. The results of present study showed that treadmill exercise increased GAP-43 and Cdc2 expression. Also, the results of present study showed that treadmill exercise decreased cavity formation. The treadmill exercise facilitated nerve regeneration in vivo by improving cell proliferation and migration, axonal sprouting and regeneration, and astrocytes after contusive spinal cord injury. It also accelerated functional recovery of hindlimb. In conclusion, the results of the present study suggest that treadmill exercise facilitates nerve regeneration and functional recovery after contusive spinal cord injury.

목차

Abstract
1. 서론
2. 연구 방법
3. 연구 결과
4. 고찰
5. 결론
감사의 글
인용문헌

참고문헌 (0)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

이 논문과 함께 이용한 논문

최근 본 자료

전체보기

댓글(0)

0

UCI(KEPA) : I410-ECN-0101-2009-590-019530076